The oxytocin receptor: from intracellular signaling to behavior

B Jurek, ID Neumann - Physiological reviews, 2018 - journals.physiology.org
The many facets of the oxytocin (OXT) system of the brain and periphery elicited nearly
25,000 publications since 1930 (see, as listed in PubMed), which revealed central roles for …

Brain oxytocin: how puzzle stones from animal studies translate into psychiatry

V Grinevich, ID Neumann - Molecular psychiatry, 2021 - nature.com
The neuropeptide oxytocin has attracted great attention of the general public, basic
neuroscience researchers, psychologists, and psychiatrists due to its profound pro-social …

Detection, processing and reinforcement of social cues: regulation by the oxytocin system

R Menon, ID Neumann - Nature Reviews Neuroscience, 2023 - nature.com
Many social behaviours are evolutionarily conserved and are essential for the healthy
development of an individual. The neuropeptide oxytocin (OXT) is crucial for the fine-tuned …

Amygdala, neuropeptides, and chronic pain-related affective behaviors

V Neugebauer, M Mazzitelli, B Cragg, G Ji… - …, 2020 - Elsevier
Neuropeptides play important modulatory roles throughout the nervous system, functioning
as direct effectors or as interacting partners with other neuropeptide and neurotransmitter …

Hypothalamic oxytocin mediates social buffering of the stress response

AS Smith, Z Wang - Biological psychiatry, 2014 - Elsevier
Background While stressful life events can enhance the risk of mental disorders, positive
social interactions can propagate good mental health and normal behavioral routines. Still …

Oxytocin attenuates amygdala reactivity to fear in generalized social anxiety disorder

I Labuschagne, KL Phan, A Wood, M Angstadt… - …, 2010 - nature.com
Patients with generalized social anxiety disorder (GSAD) exhibit heightened activation of the
amygdala in response to social cues conveying threat (eg, fearful/angry faces). The …

Acute effects of steroid hormones and neuropeptides on human social–emotional behavior: a review of single administration studies

PA Bos, J Panksepp, RM Bluthé, J Van Honk - Frontiers in …, 2012 - Elsevier
Steroids and peptides mediate a diverse array of animal social behaviors. Human research
is restricted by technical–ethical limitations, and models of the neuroendocrine regulation of …

Brain oxytocin: a key regulator of emotional and social behaviours in both females and males

ID Neumann - Journal of neuroendocrinology, 2008 - Wiley Online Library
In addition to various reproductive stimuli, the neuropeptide oxytocin (OXT) is released both
from the neurohypophysial terminal into the blood stream and within distinct brain regions in …

Vasopressin and oxytocin excite distinct neuronal populations in the central amygdala

D Huber, P Veinante, R Stoop - Science, 2005 - science.org
Vasopressin and oxytocin strongly modulate autonomic fear responses, through
mechanisms that are still unclear. We describe how these neuropeptides excite distinct …

Social buffering: relief from stress and anxiety

T Kikusui, JT Winslow, Y Mori - … Transactions of the …, 2006 - royalsocietypublishing.org
Communication is essential to members of a society not only for the expression of personal
information, but also for the protection from environmental threats. Highly social mammals …