A number of challenges in skin grafting for wound healing have drawn researchers to focus
on skin tissue engineering as an alternative solution. The core idea of tissue engineering is …

Innervation plays a pivotal role as a driver of tissue and organ development as well as a
means for their functional control and modulation. Therefore, innervation should be carefully …

Mesenchymal stem cell (MSC) transplantation is promising for repairing heart tissues post
myocardial infarction (MI). In particular, paracrine effects of the transplanted MSCs have …

One of the major challenges in the development of a larger and longer nerve conduit for
peripheral nerve repair is the limitation in oxygen and nutrient diffusion within the tissue after …

Rett syndrome (RTT), mainly caused by mutations in methyl-CpG binding protein 2
(MeCP2), is one of the most prevalent intellectual disorders without effective therapies. Here …

Artificial nerve conduits capable of adequately releasing neurotrophic factors are extensively
studied to bridge nerve defects. However, the lack of neurotrophic factors in the proximal …

Pulpal and periapical diseases are the most common dental diseases. The traditional
treatment is root canal therapy, which achieves satisfactory therapeutic outcomes …

Volumetric muscle loss (VML) is the traumatic or surgical loss of skeletal muscle beyond the
inherent regenerative capacity of the body, generally leading to severe functional deficit …

Neurotrophins (NTs) are members of a neuronal growth factor protein family whose action is
mediated by the tropomyosin receptor kinase (TRK) receptor family receptors and the p75 …

Tissue reinnervation following trauma, disease, or transplantation often presents a
significant challenge. Here, we show that the delivery of vascular endothelial growth factor …