[HTML][HTML] Recent advances in the molecular diagnostics of gastric cancer

M Kanda, Y Kodera - World Journal of Gastroenterology: WJG, 2015 - ncbi.nlm.nih.gov
Gastric cancer (GC) is the third most common cause of cancer-related death in the world,
representing a major global health issue. Although the incidence of GC is declining, the …

Frequent expression loss of Inter-alpha-trypsin inhibitor heavy chain (ITIH) genes in multiple human solid tumors: a systematic expression analysis

A Hamm, J Veeck, N Bektas, PJ Wild, A Hartmann… - BMC cancer, 2008 - Springer
Background The inter-alpha-trypsin inhibitors (ITI) are a family of plasma protease inhibitors,
assembled from a light chain–bikunin, encoded by AMBP–and five homologous heavy …

Promoter hypermethylation of the tumor-suppressor genes ITIH5, DKK3, and RASSF1A as novel biomarkers for blood-based breast cancer screening

V Kloten, B Becker, K Winner, MG Schrauder… - Breast Cancer …, 2013 - Springer
Introduction For early detection of breast cancer, the development of robust blood-based
biomarkers that accurately reflect the host tumor is mandatory. We investigated DNA …

Prognostic DNA methylation markers for hormone receptor breast cancer: a systematic review

TC de Ruijter, F van der Heide, KM Smits… - Breast Cancer …, 2020 - Springer
Background In patients with hormone receptor-positive breast cancer, differentiating
between patients with a low and a high risk of recurrence is an ongoing challenge. In current …

A urinary microRNA signature can predict the presence of bladder urothelial carcinoma in patients undergoing surveillance

N Sapre, G Macintyre, M Clarkson, H Naeem… - British journal of …, 2016 - nature.com
Background: The objective of this study was to determine whether microRNA (miRNA)
profiling of urine could identify the presence of urothelial carcinoma of the bladder (UCB) …

Enhancer RNA SLIT2 inhibits bone metastasis of breast cancer through regulating P38 MAPK/c-Fos signaling pathway

P Li, Z Lin, Q Liu, S Chen, X Gao, W Guo, F Gong… - Frontiers in …, 2021 - frontiersin.org
Background Breast cancer (BRCA) is the most common cancer in women, while the bones
are one of the most common sites of metastasis. Although new diagnostic methods or …

Sample prep for proteomics of breast cancer: proteomics and gene ontology reveal dramatic differences in protein solubilization preferences of …

LCM Ngoka - Proteome science, 2008 - Springer
Background An important step in the proteomics of solid tumors, including breast cancer,
consists of efficiently extracting most of proteins in the tumor specimen. For this purpose …

White paper: mimetics of class 2 tumor suppressor proteins as novel drug candidates for personalized cancer therapy

E Dahl, S Villwock, P Habenberger, A Choidas, M Rose… - Cancers, 2022 - mdpi.com
Simple Summary A concept is presented for a new therapeutic approach, still in its early
stages, which focuses on the phenotypic mimicry (“mimesis”) of proteins encoded by highly …

Stratification of follicular thyroid tumours using data‐independent acquisition proteomics and a comprehensive thyroid tissue spectral library

Y Sun, L Li, Y Zhou, W Ge, H Wang, R Wu… - Molecular …, 2022 - Wiley Online Library
Thyroid nodules occur in about 60% of the population. A major challenge in thyroid nodule
diagnosis is to distinguish between follicular adenoma (FA) and carcinoma (FTC). Here, we …

Gene expression profiling associated with the progression to poorly differentiated thyroid carcinomas

JM Pita, A Banito, BM Cavaco, V Leite - British journal of cancer, 2009 - nature.com
Background: Poorly differentiated thyroid carcinomas (PDTC) represent a heterogeneous,
aggressive entity, presenting features that suggest a progression from well-differentiated …