Valvular heart disease is a major cause of morbidity and mortality worldwide. Surgical valve
repair or replacement has been the standard of care for patients with valvular heart disease …

Tissue engineering (TE) is critical in oral and craniofacial reconstruction. One of the most
popular topics on the biomaterial-based tissue regeneration process may be the interaction …

Vascular tissue engineering has made prodigious progress in recent years by converging
multidisciplinary approaches. Latest technological advancements foster the development of …

Cellular transition to hypoxia following tissue injury, has been shown to improve
angiogenesis and regeneration in multiple tissues. To take advantage of this, many hypoxia …

We developed a tissue-engineered vascular graft (TEVG) for use in children and present
results of a US Food and Drug Administration (FDA)–approved clinical trial evaluating this …

Soft biological tissues compromise diverse cell types and extracellular matrix constituents,
each of which can possess individual natural configurations, material properties, and rates …

In situ tissue engineering that uses resorbable synthetic heart valve scaffolds is an
affordable and practical approach for heart valve replacement; therefore, it is attractive for …

Despite much effort, synthetic small diameter vascular grafts still face limited success due to
vascular wall thickening known as intimal hyperplasia (IH). Compliance mismatch between …

Background Tissue-engineered vascular grafts (TEVGs) have the potential to advance the
surgical management of infants and children requiring congenital heart surgery by creating …

In situ tissue engineering using bioresorbable material implants-or scaffolds-that harness
the patient's immune response while guiding neotissue formation at the site of implantation …