Advances in the relationship between respiratory viruses and asthma

SJ Romero-Tapia, CG Guzmán Priego… - Journal of Clinical …, 2023 - mdpi.com
Several studies have reported that viral infection is closely associated with the onset,
progression, and exacerbation of asthma. The purpose of this review is to summarize the …

[HTML][HTML] Therapeutic potential of vitamin D in Management of Asthma: a literature review

C Tibrewal, NS Modi, PS Bajoria, PA Dave, RK Rohit… - Cureus, 2023 - ncbi.nlm.nih.gov
Asthma, a prevalent chronic respiratory illness, affects a substantial number of individuals
worldwide, with an estimated occurrence of 358 million cases. Evidence for the benefits of …

Bioinformatic analysis of key regulatory genes in adult asthma and prediction of potential drug candidates

S Chen, J Lv, Y Luo, H Chen, S Ma, L Zhang - Molecules, 2023 - mdpi.com
Asthma is a common chronic disease that is characterized by respiratory symptoms
including cough, wheeze, shortness of breath, and chest tightness. The underlying …

A distal enhancer of GATA3 regulates Th2 differentiation and allergic inflammation

T Kumagai, A Iwata, H Furuya, K Kato, A Okabe… - Proceedings of the …, 2024 - pnas.org
Asthma is a widespread airway disorder where GATA3-dependent Type-2 helper T (Th2)
cells and group 2 innate lymphoid cells (ILC2s) play vital roles. Asthma-associated single …

Pre-asthma: a useful concept for prevention and disease-modification? A EUFOREA paper. Part 1—allergic asthma

GK Scadding, M McDonald, V Backer, G Scadding… - Frontiers in …, 2024 - frontiersin.org
Asthma, which affects some 300 million people worldwide and caused 455,000 deaths in
2019, is a significant burden to suffers and to society. It is the most common chronic disease …

Effect of air pollution on asthma

X Zhou, V Sampath, KC Nadeau - Annals of Allergy, Asthma & Immunology, 2024 - Elsevier
Asthma is a chronic inflammatory airway disease characterized by respiratory symptoms,
variable airflow obstruction, bronchial hyperresponsiveness, and airway inflammation …

Time‐dependent gene–environment interactions are essential drivers of asthma initiation and persistence

G Chatziparasidis, MR Chatziparasidi… - Pediatric …, 2024 - Wiley Online Library
Asthma is a clinical syndrome caused by heterogeneous underlying mechanisms with some
of them having a strong genetic component. It is known that up to 82% of atopic asthma has …

[HTML][HTML] YTHDF1-CLOCK axis contributes to pathogenesis of allergic airway inflammation through LLPS

J Wang, Y Zhou, M Zhang, Y Wu, Q Wu, W Su, M Xu… - Cell Reports, 2024 - cell.com
Summary N6-methyladenosine (m6A) modification has been implicated in many cell
processes and diseases. YTHDF1, a translation-facilitating m6A reader, has not been …

Associations between combined urban and lifestyle factors and respiratory health in European children

A Guillien, R Slama, S Andrusaityte, M Casas… - Environmental …, 2024 - Elsevier
Introduction Previous studies identified some environmental and lifestyle factors
independently associated with children respiratory health, but few focused on exposure …

Epigenomic partitioning of a polygenic risk score for asthma reveals distinct genetically driven disease pathways

B Stikker, L Trap, B Sedaghati-Khayat… - European …, 2024 - Eur Respiratory Soc
Background Individual differences in susceptibility to develop asthma, a heterogeneous
chronic inflammatory lung disease, are poorly understood. It remains debated whether …