Thyroid hormones are important during development of the mammalian brain, acting on
migration and differentiation of neural cells, synaptogenesis, and myelination. The actions of …

Among the most critical actions of thyroid hormone in man and other mammals are those
exerted on brain development. Severe hypothyroidism during the neonatal period leads to …

The timing of oligodendrocyte differentiation is thought to depend on an intrinsic clock in
oligodendrocyte precursor cells that counts time or cell divisions and limits precursor cell …

Thyroid hormones are of fundamental importance for brain development and essential
factors to warrant brain functions throughout life. Their actions are mediated by binding to …

The development of oligodendrocyte progenitor cells is regulated by epigenetic factors
which control their proliferation and differentiation. When oligodendrocyte progenitor cells …

Thyroid hormone plays an important role in brain development and is essential to ensure a
normal myelination. The effects of thyroid hormone are mediated by nuclear thyroid …

Congenital hypothyroidism strongly affects myelination. To assess the role of thyroid
hormone on myelin gene expression, we have studied the effect of hypothyroidism on the …

The brain's capacity to respond to changing environments via hormonal signaling is critical
to fine-tuned function. An emerging body of literature highlights a role for myelin plasticity as …

White matter injury in the premature infant leads to motor and more commonly behavioral
and cognitive problems that are a tremendous burden to society. While there has been much …

Since multiple sclerosis (MS) and autoimmune thyroiditis (AIT) are presumed to be of
autoimmune origin the correlation of these two diseases is of special interest. The aim of this …