Achieving complete understanding of any living thing inevitably requires thorough analysis
of both its anatomic and dynamic properties. Live-cell imaging experiments carried out to …

Exosomes play a pivotal role in mediating intercellular communications and package
delivery. They have recently been discovered to serve as diagnostic biomarkers as well as a …

Amorphous solids such as glass, plastics and amorphous thin films are ubiquitous in our
daily life and have broad applications ranging from telecommunications to electronics and …

Nucleation plays a critical role in many physical and biological phenomena that range from
crystallization, melting and evaporation to the formation of clouds and the initiation of …

Liquids and solids are two fundamental states of matter. However, our understanding of their
three-dimensional atomic structure is mostly based on physical models. Here we use atomic …

I introduce an algorithm for subpixel localization of imaged objects based on an analytic,
non-iterative calculation of the best-fit radial symmetry center. This approach yields tracking …

Cells release exosomes to transfer various molecules to other cells. Exosomes are involved
in a number of physiological and pathological processes. They are emerging great potential …

Cells release exosomes into extracellular medium. Although the important roles of
exosomes in many physiological and pathological processes are being revealed, the …

A multitude of cellular and subcellular processes depend critically on the mechanical
deformability of the cytoplasm. We have recently introduced the method of particle-tracking …

As a method of function approximation, polynomial fitting has always been the main
research hotspot in mathematical modeling. In many disciplines such as computer, physics …