Population differences in major functional polymorphisms of pharmacokinetics/pharmacodynamics-related genes in Eastern Asians and Europeans: implications in …
K Kurose, E Sugiyama, Y Saito - Drug metabolism and …, 2012 - jstage.jst.go.jp
Drug lag, recently discussed extensively in Japan, can be divided into two phases: clinical
development time and application review time. The former factor is still an important problem …
development time and application review time. The former factor is still an important problem …
Associations between HLA class I and cytochrome P450 2C9 genetic polymorphisms and phenytoin-related severe cutaneous adverse reactions in a Thai population
W Tassaneeyakul, N Prabmeechai… - Pharmacogenetics …, 2016 - journals.lww.com
Background Phenytoin is one of the most common causative drugs of several types of
severe cutaneous adverse reactions (SCAR) such as Stevens–Johnson syndrome (SJS) …
severe cutaneous adverse reactions (SCAR) such as Stevens–Johnson syndrome (SJS) …
High-resolution analyses of human leukocyte antigens allele and haplotype frequencies based on 169,995 volunteers from the China Bone Marrow Donor Registry …
XY Zhou, FM Zhu, JP Li, W Mao, DM Zhang, ML Liu… - PloS one, 2015 - journals.plos.org
Allogeneic hematopoietic stem cell transplantation is a widely used and effective therapy for
hematopoietic malignant diseases and numerous other disorders. High-resolution human …
hematopoietic malignant diseases and numerous other disorders. High-resolution human …
Candidate HLA genes for prediction of co-trimoxazole-induced severe cutaneous reactions
T Kongpan, S Mahasirimongkol… - Pharmacogenetics …, 2015 - journals.lww.com
Background Co-trimoxazole is a sulfonamide-containing antibiotic that is effective in the
treatment of several infections and for prophylaxis of Pneumocystis jiroveci pneumonia. This …
treatment of several infections and for prophylaxis of Pneumocystis jiroveci pneumonia. This …
Cost-Effectiveness Analysis of HLA-B*5801 Testing in Preventing Allopurinol-Induced SJS/TEN in Thai Population
S Saokaew, W Tassaneeyakul, R Maenthaisong… - PloS one, 2014 - journals.plos.org
Background Stevens-Johnson syndrome (SJS) and Toxic Epidermal Necrolysis (TEN),
caused by allopurinol therapy, are strongly associated with the human leukocyte antigen …
caused by allopurinol therapy, are strongly associated with the human leukocyte antigen …
Economic evaluation of HLA‐B* 15: 02 screening for carbamazepine‐induced severe adverse drug reactions in T hailand
W Rattanavipapong, T Koopitakkajorn… - …, 2013 - Wiley Online Library
Purpose There is strong evidence of an association between the presence of the human
leukocyte antigen (HLA)‐B* 15: 02 and two severe adverse drug reactions—S tevens‐J …
leukocyte antigen (HLA)‐B* 15: 02 and two severe adverse drug reactions—S tevens‐J …
Genetic Determinants in HLA and Cytochrome P450 Genes in the Risk of Aromatic Antiepileptic-Induced Severe Cutaneous Adverse Reactions
AF Ahmed, C Sukasem, MA Sabbah, NF Musa… - Journal of Personalized …, 2021 - mdpi.com
Adverse drug reaction (ADR) is a pressing health problem, and one of the main reasons for
treatment failure with antiepileptic drugs. This has become apparent in the event of severe …
treatment failure with antiepileptic drugs. This has become apparent in the event of severe …
Analysis of HLA A* 02 association with vaccine efficacy in the RV144 HIV-1 vaccine trial
The RV144 HIV-1 vaccine trial demonstrated partial efficacy of 31% against HIV-1 infection.
Studies into possible correlates of protection found that antibodies specific to the V1 and V2 …
Studies into possible correlates of protection found that antibodies specific to the V1 and V2 …
HLA-DRB1 and HLA-DQB1 are associated with adult-onset immunodeficiency with acquired anti-interferon-gamma autoantibodies
M Pithukpakorn, E Roothumnong, N Angkasekwinai… - Plos one, 2015 - journals.plos.org
Recently a newly identified clinical syndrome of disseminated non-tuberculous
mycobacterial diseases (with or without other opportunistic infections in adult patients who …
mycobacterial diseases (with or without other opportunistic infections in adult patients who …
HLA‐DQ association and allele competition in Chinese narcolepsy
F Han, L Lin, J Li, SX Dong, P An, L Zhao… - Tissue …, 2012 - Wiley Online Library
In Japanese, Koreans and Caucasians, narcolepsy/hypocretin deficiency is tightly
associated with the DRB1* 15: 01‐DQA1* 01: 02‐DQB1* 06: 02 haplotype. Studies in …
associated with the DRB1* 15: 01‐DQA1* 01: 02‐DQB1* 06: 02 haplotype. Studies in …