Abstract γ‐Aminobutyric acid (GABA) is the primary inhibitory neurotransmitter in the central
nervous system. GABA is converted from glutamic acid by the action of glutamic acid …

Introduction. Gamma-hydroxybutyrate (GHB) and its precursors, gamma-butyrolactone
(GBL) and 1, 4-butanediol (1, 4-BD), are drugs of abuse which act primarily as central …

Since 1975, Robert Julien's A Primer of Drug Action has been the definitive guide to the
effects of psychoactive drugs on the brain and on behavior. Now fully updated, this popular …

There has been increasing attention in the United States to problems of abuse of gamma-
hydroxybutyrate (GHB), with some evidence for problems in other parts of the world as well …

Ecstasy (MDMA), gamma-hydroxybutyrate (GHB), ketamine, and methamphetamine are 4
examples of club drugs that are increasing in popularity. Although the pharmacological …

Background: Accumulating evidence shows the efficacy of the γ‐aminobutyric acid (GABAB)
receptor agonist baclofen in reducing alcohol intake in rats, but no studies have been …

Background Chronic excessive alcohol consumption may lead to dependence, and to
alcohol withdrawal syndrome (AWS) in case of abrupt drinking cessation. Gamma …

Background 1, 4-Butanediol is an industrial solvent that, when ingested, is converted to γ-
hydroxybutyrate, a drug of abuse with depressant effects, primarily on the central nervous …

Gamma-hydroxybutyric acid (GHB) is gaining popularity as a drug of abuse. Reports of
toxicity and lethality associated with GHB use have increased. This survey study was …

Aim: To examine the clinical course of gamma-hydroxybutyrate (GHB) withdrawal and
generate management guidelines. Design: Review and analysis of all published reports of …