Transposable elements in normal and malignant hematopoiesis

E Lemerle, E Trompouki - Disease Models & Mechanisms, 2023 - journals.biologists.com
Transposable elements (TEs) are dispersed repetitive DNA sequences that can move within
a genome. Even though hundreds of years of evolution have led to the accumulation of …

Cancer-associated chromatin variants uncover the oncogenic role of transposable elements

G Grillo, M Lupien - Current Opinion in Genetics & Development, 2022 - Elsevier
The vast array of cell states found across human tissue arises from chromatin variants, which
correspond to segments of the genome, known as DNA elements, adopting a different …

Defining the Chromatin and Three Dimensional Genomic Landscape of Paediatric Brain Tumors

JJY Lee - 2022 - search.proquest.com
Abstract Medulloblastoma (MB) and Ependymoma (EPN) are among the most frequently
diagnosed malignant paediatric brain tumors. Each of these tumor types is a heterogeneous …