Eosinophilic esophagitis (EoE) is a chronic immune-mediated disease of the esophagus
characterized clinically by symptoms related to esophageal dysfunction and histologically by …

Eosinophilic gastrointestinal disorders (EGID) are characterized pathologically by excess
eosinophils in mucosal biopsies of one or multiple sites in the gastrointestinal (GI) tract …

Background Epigenetic mechanisms could alter the airway epithelial barrier and ultimately
lead to atopic diseases such as asthma. We aimed to identify DNA methylation profiles that …

The major hallmarks of Epithelial-Mesenchymal Transition (EMT) is the loss of epithelial cell
polarity and loss of expression of the cell-cell adhesion molecule like E-cadherin and …

Eosinophilic esophagitis (EoE) is a chronic, allergen-driven inflammatory disease of the
esophagus characterized predominantly by eosinophilic inflammation, leading to …

Chronic rhinosinusitis with nasal polyps is affecting up to 3% of Western populations. About
10% of patients with nasal polyps also suffer from asthma and intolerance to aspirin, a …

The traditional view of integrins portrays these highly conserved cell surface receptors as
mediators of cellular attachment to the extracellular matrix (ECM), and to a lesser degree, as …

Tourette syndrome (TS) is a neuropsychiatric disorder of complex genetic architecture
involving multiple interacting genes. Here, we sought to elucidate the pathways that underlie …

Background Eosinophilic esophagitis (EoE) is a chronic immune mediated inflammatory
disorder of the esophagus. It is still unknown why children and adults present differently, and …

Food hypersensitivity is a group of diseases arising from a specific immune response that
reproduces on exposure to a given food. The current understanding of molecular …