Applications of proteomics in ovarian cancer: dawn of a new era

A Ghose, SVN Gullapalli, N Chohan, A Bolina… - Proteomes, 2022 - mdpi.com
The ability to identify ovarian cancer (OC) at its earliest stages remains a challenge. The
patients present an advanced stage at diagnosis. This heterogeneous disease has …

Multi-omics approaches for biomarker discovery in early ovarian cancer diagnosis

Y Xiao, M Bi, H Guo, M Li - EBioMedicine, 2022 - thelancet.com
Ovarian cancer (OC) is a heterogeneous disease with the highest mortality rate and the
poorest prognosis among gynecological malignancies. Because of the absence of specific …

Circulating microRNAs: Biomarkers of disease

Y Wu, Q Li, R Zhang, X Dai, W Chen, D Xing - Clinica Chimica Acta, 2021 - Elsevier
MicroRNAs are a class of endogenous noncoding single-stranded RNA molecules with
approximately 20–24 nucleotides and are associated with a broad range of biological …

Exosomal miRNA confers chemo resistance via targeting Cav1/p-gp/M2-type macrophage axis in ovarian cancer

P Kanlikilicer, R Bayraktar, M Denizli, MH Rashed… - …, 2018 - thelancet.com
Background Circulating miRNAs are known to play important roles in intercellular
communication. However, the effects of exosomal miRNAs on cells are not fully understood …

[HTML][HTML] Integrated analysis of ascites and plasma extracellular vesicles identifies a miRNA-based diagnostic signature in ovarian cancer

W Wang, HA Jo, S Park, H Kim, SI Kim, Y Han, J Lee… - Cancer letters, 2022 - Elsevier
Ovarian cancer is mostly diagnosed at advantaged stages due to the lack of early diagnostic
biomarkers. The common metastasis pattern is characterized by peritoneal dissemination …

Liquid biopsy in ovarian cancer: the potential of circulating miRNAs and exosomes

L Giannopoulou, M Zavridou, S Kasimir-Bauer… - Translational …, 2019 - Elsevier
Ovarian cancer still remains the most lethal female cancer, since in most cases it is
diagnosed at an advanced stage. Usually after completion of primary treatment …

Circulating cell-free microRNAs as clinical cancer biomarkers

V Armand-Labit, A Pradines - Biomolecular concepts, 2017 - degruyter.com
MicroRNAs (miRNAs) are non-coding small RNAs that are master regulators of genic
expression and consequently of many cellular processes. But their expression is often …

Diagnostic potential for a serum miRNA neural network for detection of ovarian cancer

KM Elias, W Fendler, K Stawiski, SJ Fiascone… - Elife, 2017 - elifesciences.org
Recent studies posit a role for non-coding RNAs in epithelial ovarian cancer (EOC).
Combining small RNA sequencing from 179 human serum samples with a neural network …

Exosomal miR-1246 in serum as a potential biomarker for early diagnosis of gastric cancer

Y Shi, Z Wang, X Zhu, L Chen, Y Ma, J Wang… - International journal of …, 2020 - Springer
Background Gastric cancer (GC) patients are usually diagnosed in advanced stages which
results in high mortality. This study aimed to identify novel circulating miRNAs as biomarkers …

A review on the role of miR-1246 in the pathoetiology of different cancers

S Ghafouri-Fard, T Khoshbakht, BM Hussen… - Frontiers in molecular …, 2022 - frontiersin.org
miR-1246 is a microRNA firstly recognized through application of a high throughput
sequencing technique in human embryonic stem cells. Subsequent studies have shown the …