Since the beginning of the coronavirus pandemic in late 2019, viral infections have become
one of the top three causes of mortality worldwide. Immunization and the use of …

Background: The current challenge in drug development lies in addressing the
physicochemical issues that lead to low drug effectiveness. Solubility, a crucial …

Crystal morphology plays a pivotal role in the production process of pharmaceutical
compounds and influences the properties of the final product. Achieving control over crystal …

Purpose Pharmaceutical cocrystals are gaining attention from pharmaceutical industries and
researchers because of their applicability, scalability, and cost-effectiveness. During the …

Escitalopram (ETP) has poor oral bioavailability due to its low water solubility, hence the
goal of this work was to design and optimize a self-nano-emulsifying drug delivery system …

The objective of this research was to improve the solubility and dissolution rate of Efavirenz
(EFA), a BCS II drug utilized for HIV infection treatment, by cocrystallization with ascorbic …

Silymarin (SM) is a herbal medicine extracted from the plant Silybum marianum. SM has
many potent pharmacological activities among which are antioxidant, anti-inflammatory, and …

Background: The bioavailability of the drug is influenced by the solubility of the drug in the
biological fluids. Solubility and dissolution are the rate-limiting steps for the absorption and …