Nuclear physics in particle therapy: a review

M Durante, H Paganetti - Reports on Progress in Physics, 2016 - iopscience.iop.org
Charged particle therapy has been largely driven and influenced by nuclear physics. The
increase in energy deposition density along the ion path in the body allows reducing the …

A review of the use and potential of the GATE Monte Carlo simulation code for radiation therapy and dosimetry applications

D Sarrut, M Bardiès, N Boussion, N Freud… - Medical …, 2014 - Wiley Online Library
In this paper, the authors' review the applicability of the open‐source GATE Monte Carlo
simulation platform based on the GEANT4 toolkit for radiation therapy and dosimetry …

Prompt-gamma monitoring in hadrontherapy: A review

J Krimmer, D Dauvergne, JM Létang, É Testa - Nuclear Instruments and …, 2018 - Elsevier
Secondary radiation emission induced by nuclear reactions is correlated to the path of ions
in matter. Therefore, such penetrating radiation can be used for in vivo control of …

Range verification methods in particle therapy: underlying physics and Monte Carlo modeling

AC Kraan - Frontiers in oncology, 2015 - frontiersin.org
Hadron therapy allows for highly conformal dose distributions and better sparing of organs-
at-risk, thanks to the characteristic dose deposition as function of depth. However, the quality …

Distributions of secondary particles in proton and carbon-ion therapy: a comparison between GATE/Geant4 and FLUKA Monte Carlo codes

C Robert, G Dedes, G Battistoni… - Physics in Medicine …, 2013 - iopscience.iop.org
Monte Carlo simulations play a crucial role for in-vivo treatment monitoring based on PET
and prompt gamma imaging in proton and carbon-ion therapies. The accuracy of the nuclear …

Development of a Compton camera for medical applications based on silicon strip and scintillation detectors

J Krimmer, JL Ley, C Abellan, JP Cachemiche… - Nuclear Instruments and …, 2015 - Elsevier
A Compton camera is being developed for the purpose of ion-range monitoring during
hadrontherapy via the detection of prompt-gamma rays. The system consists of a scintillating …

Vision 20/20: Positron emission tomography in radiation therapy planning, delivery, and monitoring

K Parodi - Medical physics, 2015 - Wiley Online Library
Positron emission tomography (PET) is increasingly considered as an effective imaging
method to support several stages of radiation therapy. The combined usage of functional …

Medical applications of silicon photomultipliers

MG Bisogni, A Del Guerra, N Belcari - Nuclear instruments and methods in …, 2019 - Elsevier
Silicon photomultipliers (SiPMs) are becoming the reference photodetectors in many fields.
In medicine they are slowly replacing photomultiplier tubes and avalanche photodiodes in …

Applications of Machine Learning to Improve the Clinical Viability of Compton Camera Based in vivo Range Verification in Proton Radiotherapy

JC Polf, CA Barajas, SW Peterson, DS Mackin… - Frontiers in …, 2022 - frontiersin.org
We studied the application of a deep, fully connected Neural Network (NN) to process
prompt gamma (PG) data measured by a Compton camera (CC) during the delivery of …

Measurement of charged particle yields from PMMA irradiated by a 220 MeV/u 12C beam

L Piersanti, F Bellini, F Bini, F Collamati… - Physics in Medicine …, 2014 - iopscience.iop.org
The radiation used in hadrontherapy treatments interacts with the patient body producing
secondary particles, either neutral or charged, that can be used for dose and Bragg peak …