The mock circulatory loop (MCL) is an in vitro experimental system that can provide
continuous pulsatile flows and simulate different physiological or pathological parameters of …

Heart failure is a major health risk, and with limited availability of donor organs, there is an
increasing need for developing cardiac assist devices (CADs). Mock circulatory loops (MCL) …

This paper presents a novel mock circulation for the evaluation of ventricular assist devices
(VADs), which is based on a hardware-in-the-loop concept. A numerical model of the human …

Rotary left ventricular assist devices (LVADs) show weaker response to preload and greater
response to afterload than the native heart. This may lead to ventricular suction or …

Goal: This work presents the development of a Hybrid Mock Circulatory Loop (HMCL) to
simulate hemodynamics at patient-specific level in terms of both 3D geometry and …

Controlled and repeatable in vitro evaluation of cardiovascular devices using a mock
circulation loop (MCL) is essential prior to in vivo or clinical trials. MCLs often consist of only …

Mock circulation loops (MCLs) are used to evaluate cardiovascular devices prior to in-vivo
trials; however they lack the vital autoregulatory responses that occur in humans. This study …

The application of rotary left ventricular (LV) assist devices (LVAD s) is expanding from
bridge to transplant, to destination and bridge to recovery therapy. Conventional constant …

Objective In the present work a cardiovascular simulator designed both for clinical and
training use is presented. Method The core of the simulator is a lumped parameter model of …

Rotary blood pumps are emerging as a viable technology for total artificial hearts, and the
development of physiological control algorithms is accelerated with new evaluation …