Disorders of the enteric nervous system—a holistic view

B Niesler, S Kuerten, IE Demir… - … reviews Gastroenterology & …, 2021 - nature.com
The enteric nervous system (ENS) is the largest division of the peripheral nervous system
and closely resembles components and functions of the central nervous system. Although …

Symptoms and the body: taking the inferential leap

O Van den Bergh, M Witthöft, S Petersen… - … & Biobehavioral Reviews, 2017 - Elsevier
The relationship between the conscious experience of physical symptoms and indicators of
objective physiological dysfunction is highly variable and depends on characteristics of the …

British Society of Gastroenterology guidelines on the management of irritable bowel syndrome

DH Vasant, PA Paine, CJ Black, LA Houghton… - Gut, 2021 - gut.bmj.com
Irritable bowel syndrome (IBS) remains one of the most common gastrointestinal disorders
seen by clinicians in both primary and secondary care. Since publication of the last British …

A review of microbiota and irritable bowel syndrome: future in therapies

BK Rodiño-Janeiro, M Vicario, C Alonso-Cotoner… - Advances in …, 2018 - Springer
Irritable bowel syndrome (IBS), one of the most frequent digestive disorders, is characterized
by chronic and recurrent abdominal pain and altered bowel habit. The origin seems to be …

The enteric nervous system in gastrointestinal disease etiology

AM Holland, AC Bon-Frauches, D Keszthelyi… - Cellular and Molecular …, 2021 - Springer
A highly conserved but convoluted network of neurons and glial cells, the enteric nervous
system (ENS), is positioned along the wall of the gut to coordinate digestive processes and …

Functional variants in the sucrase–isomaltase gene associate with increased risk of irritable bowel syndrome

M Henström, L Diekmann, F Bonfiglio, F Hadizadeh… - Gut, 2018 - gut.bmj.com
Objective IBS is a common gut disorder of uncertain pathogenesis. Among other factors,
genetics and certain foods are proposed to contribute. Congenital sucrase–isomaltase …

[HTML][HTML] Update S3-Leitlinie Reizdarmsyndrom: Definition, Pathophysiologie, Diagnostik und Therapie. Gemeinsame Leitlinie der Deutschen Gesellschaft für …

P Layer, V Andresen, H Allescher… - Zeitschrift für …, 2021 - thieme-connect.com
Auch wurden ähnlich wie bei der Vorgängerleitlinie die Empfehlungen zum kindlichen
Reizdarmsyndrom und Empfehlungen zur Abgrenzung intestinaler Motilitätsstörungen …

New treatments and therapeutic targets for IBS and other functional bowel disorders

M Simrén, J Tack - Nature Reviews Gastroenterology & Hepatology, 2018 - nature.com
Functional bowel disorders (FBDs) are a spectrum of disorders characterized by
combinations of symptoms attributable to the lower gastrointestinal tract. Most current first …

The potential role of gut mycobiome in irritable bowel syndrome

Y Gu, G Zhou, X Qin, S Huang, B Wang… - Frontiers in …, 2019 - frontiersin.org
The human gut is inhabited by diverse microorganisms that play crucial roles in health and
disease. Gut microbiota dysbiosis is increasingly considered as a vital factor in the …

Development, diversity, and neurogenic capacity of enteric glia

W Boesmans, A Nash, KR Tasnády, W Yang… - Frontiers in Cell and …, 2022 - frontiersin.org
Enteric glia are a fascinating population of cells. Initially identified in the gut wall as the
“support” cells of the enteric nervous system, studies over the past 20 years have unveiled a …