Illuminating dendritic function with computational models
P Poirazi, A Papoutsi - Nature reviews neuroscience, 2020 - nature.com
Dendrites have always fascinated researchers: from the artistic drawings by Ramon y Cajal
to the beautiful recordings of today, neuroscientists have been striving to unravel the …
to the beautiful recordings of today, neuroscientists have been striving to unravel the …
Dendritic integration: 60 years of progress
GJ Stuart, N Spruston - Nature neuroscience, 2015 - nature.com
Understanding how individual neurons integrate the thousands of synaptic inputs they
receive is critical to understanding how the brain works. Modeling studies in silico and …
receive is critical to understanding how the brain works. Modeling studies in silico and …
Connectomic reconstruction of the inner plexiform layer in the mouse retina
Comprehensive high-resolution structural maps are central to functional exploration and
understanding in biology. For the nervous system, in which high resolution and large spatial …
understanding in biology. For the nervous system, in which high resolution and large spatial …
Feature detection by retinal ganglion cells
D Kerschensteiner - Annual review of vision science, 2022 - annualreviews.org
Retinal circuits transform the pixel representation of photoreceptors into the feature
representations of ganglion cells, whose axons transmit these representations to the brain …
representations of ganglion cells, whose axons transmit these representations to the brain …
Branch-specific dendritic Ca2+ spikes cause persistent synaptic plasticity
The brain has an extraordinary capacity for memory storage, but how it stores new
information without disrupting previously acquired memories remains unknown. Here we …
information without disrupting previously acquired memories remains unknown. Here we …
The neuronal organization of the retina
RH Masland - Neuron, 2012 - cell.com
The mammalian retina consists of neurons of> 60 distinct types, each playing a specific role
in processing visual images. They are arranged in three main stages. The first decomposes …
in processing visual images. They are arranged in three main stages. The first decomposes …
A visual motion detection circuit suggested by Drosophila connectomics
Animal behaviour arises from computations in neuronal circuits, but our understanding of
these computations has been frustrated by the lack of detailed synaptic connection maps, or …
these computations has been frustrated by the lack of detailed synaptic connection maps, or …
Space–time wiring specificity supports direction selectivity in the retina
How does the mammalian retina detect motion? This classic problem in visual neuroscience
has remained unsolved for 50 years. In search of clues, here we reconstruct Off-type …
has remained unsolved for 50 years. In search of clues, here we reconstruct Off-type …
Calcium signalling: dynamics, homeostasis and remodelling
MJ Berridge, MD Bootman, HL Roderick - Nature reviews Molecular …, 2003 - nature.com
Ca 2+ is a highly versatile intracellular signal that operates over a wide temporal range to
regulate many different cellular processes. An extensive Ca 2+-signalling toolkit is used to …
regulate many different cellular processes. An extensive Ca 2+-signalling toolkit is used to …
Wiring specificity in the direction-selectivity circuit of the retina
KL Briggman, M Helmstaedter, W Denk - Nature, 2011 - nature.com
The proper connectivity between neurons is essential for the implementation of the
algorithms used in neural computations, such as the detection of directed motion by the …
algorithms used in neural computations, such as the detection of directed motion by the …