Dengue is a major global public health problem requiring a safe and efficacious vaccine as
the foundation of a comprehensive countermeasure strategy. Despite decades of attempts …

Mortality from severe dengue is low, but the economic and resource burden on health
services remains substantial in endemic settings. Unfortunately, progress towards …

Background Aedes aegypti mosquitoes infected with the w Mel strain of Wolbachia pipientis
are less susceptible than wild-type A. aegypti to dengue virus infection. Methods We …

Background This systematic review aims to assess how different urbanisation patterns
related to rapid urban growth, unplanned expansion, and human population density affect …

Dengue is an emerging viral disease principally transmitted by the Aedes (Stegomyia)
aegypti mosquito. It is one of the fastest-growing global infectious diseases, with 100–400 …

Background A substantial unmet need remains for safe and effective vaccines against
dengue virus disease, particularly for individuals who are dengue-naive and those younger …

For decades, arboviral diseases were considered to be only minor contributors to global
mortality and disability. As a result, low priority was given to arbovirus research investment …

Background The landscape of mosquito-borne disease risk has changed dramatically in
recent decades, due to the emergence and reemergence of urban transmission cycles …

Aedes mosquito-transmitted diseases, such as dengue, Zika and chikungunya, are
becoming major global health emergencies while old threats, such as yellow fever, are re …

Background Diseases caused by Aedes-borne viruses, such as dengue, Zika, chikungunya,
and yellow fever, are emerging and reemerging globally. The causes are multifactorial and …