The signal pathways and treatment of cytokine storm in COVID-19

L Yang, X Xie, Z Tu, J Fu, D Xu, Y Zhou - Signal transduction and …, 2021 - nature.com
Abstract The Coronavirus Disease 2019 (COVID-19) pandemic has become a global crisis
and is more devastating than any other previous infectious disease. It has affected a …

Advances and utility of the human plasma proteome

EW Deutsch, GS Omenn, Z Sun, M Maes… - Journal of proteome …, 2021 - ACS Publications
The study of proteins circulating in blood offers tremendous opportunities to diagnose,
stratify, or possibly prevent diseases. With recent technological advances and the urgent …

Gut microbiome alterations and gut barrier dysfunction are associated with host immune homeostasis in COVID-19 patients

Z Sun, ZG Song, C Liu, S Tan, S Lin, J Zhu, FH Dai… - BMC medicine, 2022 - Springer
Background COVID-19 is an infectious disease characterized by multiple respiratory and
extrapulmonary manifestations, including gastrointestinal symptoms. Although recent …

[HTML][HTML] Relationship of SARS-CoV-2–specific CD4 response to COVID-19 severity and impact of HIV-1 and tuberculosis coinfection

C Riou, E Du Bruyn, C Stek… - The Journal of …, 2021 - Am Soc Clin Investig
JCI - Relationship of SARS-CoV-2–specific CD4 response to COVID-19 severity and impact of
HIV-1 and tuberculosis coinfection Go to JCI Insight About Editors Consulting Editors For authors …

Severe Glutathione Deficiency, Oxidative Stress and Oxidant Damage in Adults Hospitalized with COVID-19: Implications for GlyNAC (Glycine and N-Acetylcysteine) …

P Kumar, O Osahon, DB Vides, N Hanania, CG Minard… - Antioxidants, 2021 - mdpi.com
Humanity is battling a respiratory pandemic pneumonia named COVID-19 which has
resulted in millions of hospitalizations and deaths. COVID-19 exacerbations occur in waves …

COVIDomics: The proteomic and metabolomic signatures of COVID-19

M Costanzo, M Caterino, R Fedele, A Cevenini… - International journal of …, 2022 - mdpi.com
Omics-based technologies have been largely adopted during this unprecedented global
COVID-19 pandemic, allowing the scientific community to perform research on a large scale …

[HTML][HTML] Metabolomics in the Diagnosis and Prognosis of COVID-19

MR Hasan, M Suleiman, A Perez-Lopez - Frontiers in Genetics, 2021 - frontiersin.org
Coronavirus disease 2019 (COVID-19) pandemic triggered an unprecedented global effort
in developing rapid and inexpensive diagnostic and prognostic tools. Since the genome of …

Neutrophil metabolomics in severe COVID-19 reveal GAPDH as a suppressor of neutrophil extracellular trap formation

Y Li, JS Hook, Q Ding, X Xiao, SS Chung… - Nature …, 2023 - nature.com
Severe COVID-19 is characterized by an increase in the number and changes in the
function of innate immune cells including neutrophils. However, it is not known how the …

Obesity and its impact on COVID-19

AJM de Leeuw, MAM Oude Luttikhuis… - Journal of Molecular …, 2021 - Springer
The severe acute respiratory syndrome-coronavirus-2 (SARS-CoV-2) pandemic has proven
a challenge to healthcare systems since its first appearance in late 2019. The global spread …

Metabolic perturbation associated with COVID-19 disease severity and SARS-CoV-2 replication

S Krishnan, H Nordqvist, AT Ambikan, S Gupta… - Molecular & Cellular …, 2021 - ASBMB
Viruses hijack host metabolic pathways for their replicative advantage. In this study, using
patient-derived multiomics data and in vitro infection assays, we aimed to understand the …