Facing the challenges in the COVID-19 pandemic era: from standard treatments to the umbilical cord-derived mesenchymal stromal cells as a new therapeutic strategy

E Russo, S Corrao, F Di Gaudio, G Alberti, M Caprnda… - Cells, 2023 - mdpi.com
Coronavirus disease 2019 (COVID-19), the pandemic caused by severe acute respiratory
syndrome coronavirus 2 (SARS-CoV-2), which counts more than 650 million cases and …

Mesenchymal stem cells: an excellent candidate for the treatment of diabetes mellitus

Q Huang, Y Huang, J Liu - International Journal of …, 2021 - Wiley Online Library
Mesenchymal stem cells (MSCs) are adult stem cells (ASCs) known for repairing damaged
cells, exerting anti‐inflammatory responses and producing immunoregulatory effects that …

[HTML][HTML] Scaffold-free 3D culturing enhance pluripotency, immunomodulatory factors, and differentiation potential of Wharton's jelly-mesenchymal stem cells

G Thakur, EY Bok, SB Kim, CH Jo, SJ Oh… - European Journal of …, 2022 - Elsevier
Mesenchymal stem cells (MSCs) show a decline in pluripotency and differentiation with
increased cell culture passages in 2D cultures. The 2D monolayer culture fails to correctly …

[HTML][HTML] Human umbilical cord mesenchymal stem cells in diabetes mellitus and its complications: applications and research advances

L Li, J Li, H Guan, H Oishi, S Takahashi… - International Journal of …, 2023 - ncbi.nlm.nih.gov
Diabetes mellitus and its complications pose a major threat to global health and affect the
quality of life and life expectancy of patients. Currently, the application of traditional …

Stem cells as a potential therapy for diabetes mellitus: a call-to-action in Latin America

MA Solis, I Moreno Velásquez, R Correa… - Diabetology & metabolic …, 2019 - Springer
Latin America is a fast-growing region that currently faces unique challenges in the
treatment of all forms of diabetes mellitus. The burden of this disease will be even greater in …

In vitro differentiation of single donor derived human dental mesenchymal stem cells into pancreatic β cell-like cells

SB Shivakumar, HJ Lee, YB Son, D Bharti… - Bioscience …, 2019 - portlandpress.com
The present study was carried out to investigate and compare the in vitro differentiation
potential of mesenchymal stem cells (MSCs) isolated from human dental tissues (pulp …

The molecular regulatory mechanism in multipotency and differentiation of Wharton's jelly stem cells

L Ma, X He, Q Wu - International Journal of Molecular Sciences, 2023 - mdpi.com
Wharton's jelly-derived mesenchymal stem cells (WJ-MSCs) are isolated from Wharton's
jelly tissue of umbilical cords. They possess the ability to differentiate into lineage cells of …

Spare parts from discarded materials: Fetal annexes in regenerative medicine

G Gaggi, P Izzicupo, A Di Credico, S Sancilio… - International Journal of …, 2019 - mdpi.com
One of the main aims in regenerative medicine is to find stem cells that are easy to obtain
and are safe and efficient in either an autologous or allogenic host when transplanted. This …

Small molecule-induced pancreatic β-like cell development: mechanistic approaches and available strategies

G Thakur, HJ Lee, RH Jeon, SL Lee… - International Journal of …, 2020 - mdpi.com
Diabetes is a metabolic disease which affects not only glucose metabolism but also lipid and
protein metabolism. It encompasses two major types: type 1 and 2 diabetes. Despite the …

Comparative study of three types of mesenchymal stem cell to differentiate into pancreatic β‑like cells in vitro

Y Mo, Z Wang, J Gao, Y Yan… - Experimental and …, 2021 - spandidos-publications.com
Type 1 diabetes (TID) is a chronic metabolic disease where the body produces insufficient or
no insulin. Stem cells with multi‑directional differentiation potential are transplanted and …