Annexins constitute an evolutionary conserved multigene protein superfamily characterized
by their ability to interact with biological membranes in a calcium dependent manner. They …

This review provides a critical and thorough overview of the radiopharmaceutical
development and in vivo evaluation of all apoptosis-detecting radioligands that have …

Background Lower-grade glioma (LGG) is a highly heterogeneous disease that presents
challenges in accurately predicting patient prognosis. Mitochondria play a central role in the …

Phagocytic clearance of degenerating dendrites or axons is critical for maintaining tissue
homeostasis and preventing neuroinflammation. Externalized phosphatidylserine (PS) has …

Routine manipulation of the mouse genome has become a landmark in biomedical
research. Traits that are only associated with advanced developmental stages can now be …

Abstract Annexin A5 (Anxa5) promotes pancreatic adenocarcinoma, sarcoma,
tumorigenesis and progression of breast cancer and prostate cancer stem cells. It is involved …

Annexins are a family of structurally related, Ca 2+-sensitive proteins that bind to negatively
charged phospholipids and establish specific interactions with other lipids and lipid …

Annexins are a highly conserved protein family that bind to phospholipids in a calcium (Ca
2+)–dependent manner. Studies with purified annexins, as well as overexpression and …

Phagoptosis is a frequently occurring nonautonomous cell death pathway in which
phagocytes eliminate viable cells. While it is thought that phosphatidylserine (PS)“eat-me” …

To characterize gene expression in activated mast cells more comprehensively than
heretofore, we surveyed the changes in genetic transcripts by the method of serial analysis …