Zinc is a critical component in a number of conserved processes that regulate female germ
cell growth, fertility, and pregnancy. During follicle development, a sufficient intracellular …

Background Human amniotic epithelial cells (hAECs) are attractive candidates for
regenerative medical therapy, with the potential to replace deficient cells and improve …

Follicles consist of specialized somatic cells that encase a single oocyte. Follicle
development is a process regulated by a variety of endocrine, paracrine, and secretory …

Ovarian hyperstimulation syndrome (OHSS) is one of the most serious and iatrogenic
complications that can occur during in vitro fertilization treatment. Although the pathogenesis …

Radiotherapy is one of the most relevant treatment modalities for various types of
malignancies. However, it causes premature ovarian failure (POF) and subsequent infertility …

Objective To investigate the biological role of growth differentiation factor 8 (GDF8) in the
regulation of steroidogenesis in human granulosa-lutein (hGL) cells. Design Experimental …

Melatonin is present in mammalian follicular fluid and plays an important role in regulating
steroidogenesis in follicular cells. In this study, we report the effect of melatonin on …

Background Heparin-binding epidermal growth factor-like growth factor (HB-EGF) belongs
to the epidermal growth factor (EGF) family of growth factors. HB-EGF and its receptors …

Polycystic ovary syndrome (PCOS) is one of the most common endocrine disorders in
reproductive-age women. Reduced progesterone levels are associated with luteal phase …

STUDY QUESTION Does transforming growth factor-β1 (TGF-β1) up-regulate connexin43
(Cx43) to promote cell–cell communication in human granulosa cells? SUMMARY ANSWER …