Obesity predisposes individuals to the development of insulin resistance in skeletal muscle
and the liver, and researchers have recently proposed two mechanisms by which excess …

Eukaryotic organisms as well as some prokaryotes and viruses contain sphingolipids, which
are defined by a common structural feature, ie, a “sphingoid base” backbone such as D …

Obesity and dyslipidemia are risk factors for metabolic disorders including diabetes and
cardiovascular disease. Sphingolipids such as ceramide and glucosylceramides, while …

Human breast milk is the optimal source of nutrition for infant growth and development.
Breast milk fats and their downstream derivatives of fatty acids and fatty acid-derived …

The enucleate layer of the epidermis, ie the stratum corneum, is responsible for certain
critical protective functions, such as epidermal permeability barrier function. Within the …

Sphingolipids in the membranes of neurons play important roles in signal transduction,
either by modulating the localization and activation of membrane-associated receptors or by …

Sphingomyelin is found in plasma membranes and related organelles (such as endocytic
vesicles and lysosomes) of all tissues, as well as in lipoproteins. Abnormalities in …

Dietary sphingomyelin (SM) is hydrolyzed by intestinal alkaline sphingomyelinase and
neutral ceramidase to sphingosine, which is absorbed and converted to palmitic acid and …

Polar lipids including glycerophospholipids and sphingophospholipids are important
nutrients and milk is a major source, particularly for infants. This systematic review describes …

We reported previously that egg sphingomyelin (SM) inhibits the intestinal absorption of
cholesterol and fat in rats. This study was conducted to compare the relative efficiencies of …