Mapping the complex and dense arrangement of cells and their connectivity in brain tissue
demands nanoscale spatial resolution imaging. Super-resolution optical microscopy excels …

Recent advances in volume electron microscopy (EM) have been driving our thorough
understanding of the brain architecture. Volume EM becomes increasingly powerful when …

The hippocampus is a center for spatial and episodic memory formation in rodents.
Understanding the composition of subregions and circuitry maps of the hippocampus is …

Synaptic cell-adhesion molecules (CAMs) organize the architecture and properties of neural
circuits. However, whether synaptic CAMs are involved in activity-dependent remodeling of …

Structural and functional plasticity of synapses are critical neuronal mechanisms underlying
learning and memory. While activity-dependent regulation of synaptic strength has been …

Missense variants in Kirrel3 are repeatedly identified as risk factors for autism spectrum
disorder and intellectual disability, but it has not been reported if or how these variants …

Mapping the complex and dense arrangement of cells and their connectivity in brain tissue
demands nanoscale spatial resolution imaging. Super-resolution optical microscopy excels …

Adhesion molecules of the immunoglobulin superfamily (IgSF) are essential for neuronal
synapse development across evolution and control various aspects of synapse formation …

The neural cell adhesion molecule 2 (NCAM2) regulates axonal organization in the central
nervous system via mechanisms that have remained poorly understood. We now show that …

Although evidence indicates that the adult brain retains a considerable capacity for circuit
formation, adult wiring has not been broadly considered and remains poorly understood. In …