Synthetic molecular probes, chemosensors, and nanosensors used in combination with
innovative assay protocols hold great potential for the development of robust, low-cost, and …

Pancreatic cancer is a highly malignant digestive system tumor with a poor prognosis. Most
pancreatic cancer patients are diagnosed at an advanced stage or even metastasis due to …

The balance of programmed death-1 (PD-1)-expressing CD8+ T cells and regulatory T
(Treg) cells in the tumor microenvironment (TME) determines the clinical efficacy of PD-1 …

Background Metabolomics is the study of metabolome which describes the full repertoire of
small molecules, and the analysis of salivary metabolomics may help in identifying tumor …

The metabolome offers a dynamic, comprehensive, and precise picture of the phenotype.
Current high-throughput technologies have allowed the discovery of relevant metabolites …

The article starts with a brief history of discovery of cancer biomarkers followed by statistical
data on published cancer biomarkers detection strategies in the last decade to demonstrate …

Intestinal microbiota-derived metabolites have biological importance for the host.
Polyamines, such as putrescine and spermidine, are produced by the intestinal microbiota …

In this review, we provide an update on the current and future applications of saliva for
diagnostic purposes. There are many advantages of using saliva as a biofluid. Its collection …

Metabolomics, which is the metabolites profiling in biological matrices, is a key tool for
biomarker discovery and personalized medicine and has great potential to elucidate the …

Oral cancers are the sixth most frequent cancer with a high mortality rate. Oral squamous
cell carcinoma accounts for more than 90% of all oral cancers. Standard methods used to …