BACKGROUND Depression and anxiety disorders are together responsible for 8% of years
lived with disability globally. Contrary to widely held preconceptions, these are not diseases …

Timely and efficient removal of xenobiotics and metabolites from the brain is crucial in
maintaining the homeostasis and normal function of the brain. The choroid plexus (CP) …

Three conditions were established to investigate the effects of ventilation and related
ventilation noise on sleep quality: No mechanical ventilation/low noise (A); Mechanical …

Background Most adult patients with depression complain about sleep symptoms, including
insufficient and excessive sleep. However, previous studies investigating the impact of sleep …

Wakefulness levels modulate estimates of functional connectivity (FC), and, if unaccounted
for, can become a substantial confound in resting-state fMRI. Unfortunately, wakefulness is …

Objective Recently published studies have described slow spontaneous cerebral blood flow
(CBF) and cerebrospinal fluid (CSF) oscillations measured by magnetic resonance imaging …

Circadian rhythm is an intrinsic mechanism developed by organisms to adapt to external
environmental signals. Nowadays, owing to the job and after-work entertainment, staying up …

Since glymphatic was proposed and meningeal lymphatic was discovered, MRI and even
PET were introduced to investigate brain parenchymal interstitial fluid (ISF), cerebrospinal …

Cryptococcus neoformans is an opportunistic, neurotropic, and encapsulated fungus that
causes life-threatening cryptococcal meningitis (CM), especially in regions of the world …

Objective/background Sleep-wake dysfunction is bidirectionally associated with the
incidence and evolution of acute stroke. It remains unclear whether sleep disturbances are …