Cardiac fibroblasts are the primary cell type responsible for deposition of extracellular matrix
in the heart, providing support to the contracting myocardium and contributing to a myriad of …

Primary cardiac fibroblast (CF) tissue culture is a necessary tool for interrogating specific
signaling mechanisms that dictate the phenotypic heterogeneity observed in vivo in different …

Subepithelial fibrosis is a component of the remodeling observed in the bronchial wall of
patients diagnosed with asthma. In this process, human bronchial fibroblasts (HBFs) drive …

Connexins (Cx) are members of a protein family which enable extracellular and intercellular
communication through hemichannels and gap junctions (GJ), respectively. Cx take part in …

Atrial fibrillation (AF) is the most common cardiac arrhythmia, largely associated to morbidity
and mortality. Over the past decades, research in appearance and progression of this …

Gap junctions are the main form of interaction between cardiomyocytes, through which the
electrochemical activities between cardiomyocytes can be synchronized to maintain the …