As the most dominant cell type in the skin, keratinocytes play critical roles in wound repair
not only as structural cells but also exerting important immune functions. This review focuses …

Toll-like receptor (TLR)-7 is an endosomal innate immune sensor capable of detecting
single-stranded ribonucleic acid. TLR7-mediated induction of type I interferon and other …

Importance Severe coronavirus disease 2019 (COVID-19) can occur in younger,
predominantly male, patients without preexisting medical conditions. Some individuals may …

The discovery of the TLRs family and more precisely its functions opened a variety of gates
to modulate immunological host responses. TLRs 7/8 are located in the endosomal …

This review focuses primarily on the beneficial effects for human health of exposure to
ultraviolet radiation (UVR). UVR stimulates anti-inflammatory and immunosuppressive …

Coronavirus disease 2019 (COVID-19), caused by severe acute respiratory syndrome
coronavirus 2 (SARS-CoV-2), has been responsible for a devastating pandemic since March …

Background Aberrant toll-like receptors (TLRs) 7, 8, and 9 activation by self-nucleic acids is
implicated in immune-mediated inflammatory diseases (IMIDs) such as psoriasis. In …

Psoriasis is considered to be a systemic disease of immune dysfunction. It is still unclear
what triggers the inflammatory cascade associated with psoriasis but recent evidences …

LL37 is produced by skin injury and bacterial infection and plays an important role in the
early stages of psoriasis. In particular, the intracellular receptors toll-like receptors (TLR) 3 …

Abstract Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV2) is the causative
agent of Corona Virus Disease 2019 (COVID-19). Lower production of type I and III …