Depression is a common, devastating illness. Current pharmacotherapies help many
patients, but high rates of a partial response or no response, and the delayed onset of the …

Depression is the leading cause of disability worldwide, and its prevalence is 2 times higher
in women than in men. There is, however, a lack of data on sex-specific pathophysiology of …

Sex differences have been observed across many psychiatric diseases, especially mood
disorders. For major depression, the most prevalent psychiatric disorder, females show a …

Sleep disturbances increase in prevalence during the menopausal transition, with the most
common complaint being nighttime awakenings. 1, 2 Sleep disturbances impact health …

Estrogens exert profound effects on the expression of anxiety in humans and rodents;
however, the directionality of these effects varies considerably within both clinical and …

Millions of women worldwide use oral contraceptives ('the pill'; OCs), often starting at a
pubertal age when their brains are in a crucial developmental stage. Research into the …

Depression and anxiety disorders carry a tremendous worldwide burden and emerge as a
significant cause of disability among western societies. Both disorders are known to …

Background: In women, changes in estrogen levels may increase the incidence and/or
symptomatology of depression and affect the response to antidepressant treatments …

Along with the typical biochemical alterations that occur during pregnancy, certain metabolic
changes might be associated with the development of several psychiatric disorders …

Rationale Resveratrol (RSV) has been indicated to exhibit beneficial effects on depression
and anxiety treatment by suppression of inflammatory processes. Depression triggered by …