Both aging and cancer are characterized by a series of partially overlapping" hallmarks" that
we subject here to a meta-analysis. Several hallmarks of aging (ie, genomic instability …

Differentiation Syndrome (DS) has been identified in a subset of patients undergoing
treatment with novel classes of differentiating therapies for acute myeloid leukemia (AML) …

Telomeres compose the end portions of human chromosomes, and their main function is to
protect the genome. In hematological disorders, telomeres are shortened, predisposing to …

Telomere length (TL) has been associated with several health conditions including cancer.
To quantify the effect of TL on outcomes in malignancies and explore the role of type of TL …

Introduction: Obstructive sleep apnea (OSA) is a worldwide breathing disorder that has been
diagnosed globally in almost 1 billion individuals aged 30–69 years. It is characterized by …

Telomeres at the ends of linear chromosomes protect the genome. Telomeres shorten with
each round of cell division, placing a finite limit on cell growth. Telomere attrition is …

Telomere elongation is protective of genomic stability, whereas telomere shortening
increases genomic instability and thereby increases cancer risk. Long telomeres lower the …

Abstract hTERT component is the key regulator of telomerase. Alternatively spliced variants
of hTERT generate different telomerase activity. The goal of the study was to determine the …

Objective Short telomere length is a known risk factor for developing clonal haematopoietic
stem cell disorders, probably due to chromosomal instability. We tested the hypotheses that …

Introduction The current framework for risk stratification is still insufficient for highly
heterogeneous intermediate‐risk acute myeloid leukemia (IRC‐AML), which lacks specific …