Pyrazines: Synthesis and industrial application of these valuable flavor and fragrance compounds

FB Mortzfeld, C Hashem, K Vranková… - Biotechnology …, 2020 - Wiley Online Library
Alkyl pyrazines—other than being extracted from various natural sources such as coffee
beans, cocoa beans, and vegetables—can be synthesized by chemical methods or by …

Seeking heterocyclic scaffolds as antivirals against dengue virus

S De, B Aamna, R Sahu, S Parida, SK Behera… - European Journal of …, 2022 - Elsevier
Dengue is one of the most typical viral infection categorized in the Neglected Tropical
Diseases (NTDs). It is transmitted via the female Aedes aegypti mosquito to humans and …

Bayesian optimization as a sustainable strategy for early-stage process development? A case study of Cu-catalyzed C–N coupling of sterically hindered pyrazines

E Braconi, E Godineau - ACS Sustainable Chemistry & …, 2023 - ACS Publications
Bayesian optimization is a powerful machine learning technique that is particularly well-
suited for optimizing chemical reactions in the early stages of process development. It can …

Microwave-assisted synthesis–catalytic applications in aqueous media

AK Rathi, MB Gawande, R Zboril, RS Varma - Coordination Chemistry …, 2015 - Elsevier
The development of sustainable methods directed towards the synthesis of molecules is due
to the heightened awareness and recognition of alternative eco-friendly and economical …

[HTML][HTML] Safety assessment of a novel marine multi-stress-tolerant yeast Meyerozyma guilliermondii GXDK6 according to phenotype and whole genome-sequencing …

X Mo, M Zhou, Y Li, L Yu, H Bai, P Shen, X Zhou… - Food Science and …, 2024 - Elsevier
The application of microorganisms as probiotics is limited due to lack of safety evaluation.
Here, a novel multi-stress-tolerant yeast Meyerozyma guilliermondii GXDK6 with aroma …

Synthesis, characterization of some pyrazine derivatives as anti-cancer agents: In vitro and in Silico approaches

ES Tantawy, AM Amer, EK Mohamed… - Journal of Molecular …, 2020 - Elsevier
In continuation of our interest on the synthesis of fused quinoxalines and pyrazines
derivatives and due to the resultant pharmacological interest in compounds which belong to …

Medicinal chemistry perspective of fused isoxazole derivatives

MA Barmade, PR Murumkar… - Current Topics in …, 2016 - ingentaconnect.com
Nitrogen containing heterocyclic rings with an oxygen atom is considered as one of the best
combination in medicinal chemistry due to their diversified biological activities. Isoxazole, a …

Multifaceted functionalities constructed from pyrazine-based AIEgen system

M Chen, A Qin, JWY Lam, BZ Tang - Coordination Chemistry Reviews, 2020 - Elsevier
Research on aggregation-induced emission luminogens (AIEgens) has caused tremendous
research enthusiasms among scientists worldwide because they can realize strong solid …

The Volatile Organic Compounds of Streptomyces spp.: An In-Depth Analysis of Their Antifungal Properties

L Cuervo, S Álvarez-García, JA Salas, C Méndez… - Microorganisms, 2023 - mdpi.com
The study of volatile organic compounds (VOCs) has expanded because of the growing
need to search for new bioactive compounds that could be used as therapeutic alternatives …

Pyrazine derivatives: a patent review (June 2012–present)

M Dolezal, J Zitko - Expert opinion on therapeutic patents, 2015 - Taylor & Francis
Introduction: Pyrazine is a member of 1, 4-diazines, which constitute an important class of
heterocycles. Various pyrazine derivatives have been synthesized and successfully …