malERA: an updated research agenda for malaria elimination and eradication

RN Rabinovich, C Drakeley, AA Djimde, BF Hall… - PLoS …, 2017 - journals.plos.org
Achieving a malaria-free world presents exciting scientific challenges as well as
overwhelming health, equity, and economic benefits. WHO and countries are setting …

Poor-quality antimalarial drugs in southeast Asia and sub-Saharan Africa

GML Nayyar, JG Breman, PN Newton… - The Lancet infectious …, 2012 - thelancet.com
Poor-quality antimalarial drugs lead to drug resistance and inadequate treatment, which
pose an urgent threat to vulnerable populations and jeopardise progress and investments in …

Antimalarial drug resistance: a review of the biology and strategies to delay emergence and spread

EY Klein - International journal of antimicrobial agents, 2013 - Elsevier
The emergence of resistance to former first-line antimalarial drugs has been an unmitigated
disaster. In recent years, artemisinin class drugs have become standard and they are …

Drug‐resistant malaria− an insight

JE Hyde - The FEBS journal, 2007 - Wiley Online Library
Despite intensive research extending back to the 1930s, when the first synthetic antimalarial
drugs made their appearance, the repertoire of clinically licensed formulations remains very …

hmmIBD: software to infer pairwise identity by descent between haploid genotypes

SF Schaffner, AR Taylor, W Wong, DF Wirth… - Malaria journal, 2018 - Springer
Background A number of recent malaria studies have used identity by descent (IBD) to study
epidemiological processes relevant to malaria control. In this paper, a software package …

[图书][B] Global report on antimalarial drug efficacy and drug resistance: 2000-2010

World Health Organization - 2010 - apps.who.int
BACkground Plasmodium resistance to antimalarial medicines is one of the major obstacles
in the fight against malaria. Comprehensive, up-to-date understanding of the scope of …

Quantifying connectivity between local Plasmodium falciparum malaria parasite populations using identity by descent

AR Taylor, SF Schaffner, GC Cerqueira… - PLoS …, 2017 - journals.plos.org
With the rapidly increasing abundance and accessibility of genomic data, there is a growing
interest in using population genetic approaches to characterize fine-scale dispersal of …

Return of chloroquine-susceptible falciparum malaria in Malawi was a reexpansion of diverse susceptible parasites

MK Laufer, S Takala-Harrison… - The Journal of …, 2010 - academic.oup.com
The spread of drug-resistant Plasmodium falciparum malaria has been a major impediment
to malaria control and threatens prospects for elimination. We recently demonstrated the …

Multiple Origins and Regional Dispersal of Resistant dhps in African Plasmodium falciparum Malaria

RJ Pearce, H Pota, MSB Evehe, EH Bâ… - PLoS …, 2009 - journals.plos.org
Background Although the molecular basis of resistance to a number of common antimalarial
drugs is well known, a geographic description of the emergence and dispersal of resistance …

Poor quality vital anti-malarials in Africa-an urgent neglected public health priority

PN Newton, MD Green, DC Mildenhall, A Plançon… - Malaria journal, 2011 - Springer
Background Plasmodium falciparum malaria remains a major public health problem. A vital
component of malaria control rests on the availability of good quality artemisinin-derivative …