Caveolae are submicroscopic, plasma membrane pits that are abundant in many
mammalian cell types. The past few years have seen a quantum leap in our understanding …

The adhesive interactions of cells with their environment through the integrin family of
transmembrane receptors have key roles in regulating multiple aspects of cellular …

Integrins are a family of heterodimeric receptors that bind to components of the extracellular
matrix and influence cellular processes as varied as proliferation and migration. These …

Detailed information about the replication cycle of viruses and their interactions with host
organisms is required to develop strategies to stop them. Cell biology studies, live-cell …

Membrane rafts are dynamic, small (10–200 nm) domains enriched with cholesterol and
sphingolipids that compartmentalize cellular processes. Rafts participate in roles essential to …

Tetraspanins comprise a large superfamily of cell surface-associated membrane proteins
characterized by four transmembrane domains. They participate in a variety of cellular …

Once engaged by soluble or matrix-anchored ligands, cell surface proteins are commonly
sorted to lysosomal degradation through several endocytic pathways. Defective vesicular …

Since it has become clear that adhesion receptors are trafficked through the endosomal
pathway and that this can influence their function, much effort has been invested in obtaining …

The collagen family of extracellular matrix proteins has played a fundamental role in the
evolution of multicellular animals. At the present, 28 triple helical proteins have been named …

What could be a better way to study virus trafficking than'miniaturizing oneself'and'taking a
ride with the virus particle'on its journey into the cell? Single-virus tracking in living cells …