Opioid use disorder (OUD) is a chronic relapsing disorder that, whilst initially driven by
activation of brain reward neurocircuits, increasingly engages anti-reward neurocircuits that …

Opioid addiction is associated with excess mortality, morbidities, and other adverse
conditions. Guided by a life-course framework, we review the literature on the long-term …

The addiction field's failure to achieve consensus on a definition of “recovery” from severe
and persistent alcohol and other drug problems undermines clinical research, compromises …

This article reviews progress in adapting addiction treatment to respond more fully to the
chronic nature of most patients' problems. After reviewing evidence that the natural history of …

Historically, addiction treatments have been delivered and evaluated under an acute‐care
format. Fixed amounts or durations of treatment have been provided and their effects …

This article discusses the life course perspective on drug use, including conceptual and
analytic issues involved in developing the life course framework to explain how drug use …

While addiction is increasingly recognized as a chronic condition, little information is
available on the actual duration of addiction and treatment careers. The purpose of this …

Jazz saxophonist Sonny Rollins was 21 years old when his addiction to heroin threatened to
end his budding musical career, just at a point when he was breaking in with the top jazz …

Aims. This study examined client motivation as a predictor of retention and therapeutic
engagement across the major types of treatment settings represented in the third national …

Aim This study examines whether there is a minimum threshold, continuous or non‐linear
relationship between the duration of addiction treatment and improvements in drug use …