Aging is a biological process characterized by a progressive functional decline in tissues
and organs, which eventually leads to mortality. Telomeres, the repetitive DNA repeat …

Telomere shortening to a critical length can trigger aging and shorter life spans in mice and
humans by a mechanism that involves induction of a persistent DNA damage response at …

Cognitive frailty (CF) is the conjunction of cognitive impairment without dementia and
physical frailty. While predictors of each element are well-researched, mechanisms of their …

Short telomeres trigger age-related pathologies and shorter lifespans in mice and humans.
In the past, we generated mouse embryonic (ES) cells with longer telomeres than normal …

Simple Summary Age-related cardiovascular disease is the foremost cause of death
globally. Despite medical advances, we have been unable to stop or reverse the underlying …

The concept of food and aging is of great concern to humans. So far, more than 300 theories
of aging have been suggested, and approaches based on these principles have been …

Telomeres are major contributors to cell fate and aging through their involvement in cell
cycle arrest and senescence. The accelerated attrition of telomeres is associated with aging …

Antibodies are essential to immune homeostasis due to their roles in neutralizing
pathogenic agents. However, failures in central and peripheral checkpoints that eliminate …

Cancer survivors undergone treatment face an increased risk of developing atherosclerotic
cardiovascular disease (CVD), yet the underlying mechanisms remain elusive. Recent …

Aging is an unavoidable process marked by numerous physiological and psychological
changes that profoundly impact overall health and quality of life. As the global population …