Phytocannabinoids and schizophrenia: Focus on adolescence as a critical window of enhanced vulnerability and opportunity for treatment
The recent shift in socio-political debates and growing liberalization of Cannabis use across
the globe has raised concern regarding its impact on vulnerable populations such as …
the globe has raised concern regarding its impact on vulnerable populations such as …
Is cannabidiol during neurodevelopment a promising therapy for schizophrenia and autism spectrum disorders?
CM Loss, L Teodoro, GD Rodrigues… - Frontiers in …, 2021 - frontiersin.org
Schizophrenia and autism spectrum disorders (ASD) are psychiatric neurodevelopmental
disorders that cause high levels of functional disabilities. Also, the currently available …
disorders that cause high levels of functional disabilities. Also, the currently available …
Extracellular free water elevations are associated with brain volume and maternal cytokine response in a longitudinal nonhuman primate maternal immune activation …
Maternal infection has emerged as an important environmental risk factor for
neurodevelopmental disorders, including schizophrenia and autism spectrum disorders …
neurodevelopmental disorders, including schizophrenia and autism spectrum disorders …
Maternal immune activation during pregnancy alters postnatal brain growth and cognitive development in nonhuman primate offspring
Human epidemiological studies implicate exposure to infection during gestation in the
etiology of neurodevelopmental disorders. Animal models of maternal immune activation …
etiology of neurodevelopmental disorders. Animal models of maternal immune activation …
Altered dopamine D3 receptor gene expression in MAM model of schizophrenia is reversed by peripubertal cannabidiol treatment
Gestational methylazoxymethanol acetate (MAM) treatment produces offspring with adult
phenotype relevant to schizophrenia, including positive-and negative-like symptoms …
phenotype relevant to schizophrenia, including positive-and negative-like symptoms …
[HTML][HTML] Maternal immune activation during pregnancy impacts on brain structure and function in the adult offspring
S Kreitz, A Zambon, M Ronovsky, L Budinsky… - Brain, Behavior, and …, 2020 - Elsevier
Gestational infection constitutes a risk factor for the occurrence of psychiatric disorders in the
offspring. Activation of the maternal immune system (MIA) with subsequent impact on the …
offspring. Activation of the maternal immune system (MIA) with subsequent impact on the …
The Poly I: C maternal immune stimulation model shows unique patterns of brain metabolism, morphometry, and plasticity in female rats
M Casquero-Veiga, N Lamanna-Rama… - Frontiers in Behavioral …, 2023 - frontiersin.org
Introduction: Prenatal infections are associated with an increased risk of the onset of
schizophrenia. Rodent models of maternal immune stimulation (MIS) have been extensively …
schizophrenia. Rodent models of maternal immune stimulation (MIS) have been extensively …
Gestational poly (I: C) attenuates, not exacerbates, the behavioral, cytokine and mTOR changes caused by isolation rearing in a rat 'dual-hit'model for …
JY Goh, SE O'Sullivan, SE Shortall, N Zordan… - Brain, Behavior, and …, 2020 - Elsevier
Many psychiatric illnesses have a multifactorial etiology involving genetic and environmental
risk factors that trigger persistent neurodevelopmental impairments. Several risk factors have …
risk factors that trigger persistent neurodevelopmental impairments. Several risk factors have …
Gender-specific approach in psychiatric diseases: because sex matters
A Franceschini, L Fattore - European journal of pharmacology, 2021 - Elsevier
In both animals and human beings, males and females differ in their genetic background
and hormonally driven behaviour and show sex-related differences in brain activity and …
and hormonally driven behaviour and show sex-related differences in brain activity and …
The thalamic midline nucleus reuniens: potential relevance for schizophrenia and epilepsy
MJ Dolleman-van Der Weel, MP Witter - Neuroscience & Biobehavioral …, 2020 - Elsevier
Anatomical, electrophysiological and behavioral studies in rodents have shown that the
thalamic midline nucleus reuniens (RE) is a crucial link in the communication between …
thalamic midline nucleus reuniens (RE) is a crucial link in the communication between …