[HTML][HTML] Ketogenic diets and chronic disease: weighing the benefits against the risks

L Crosby, B Davis, S Joshi, M Jardine, J Paul… - Frontiers in …, 2021 - frontiersin.org
Very-low-carbohydrate ketogenic diets have been long been used to reduce seizure
frequency and more recently have been promoted for a variety of health conditions …

Multi-dimensional roles of ketone bodies in fuel metabolism, signaling, and therapeutics

P Puchalska, PA Crawford - Cell metabolism, 2017 - cell.com
Ketone body metabolism is a central node in physiological homeostasis. In this review, we
discuss how ketones serve discrete fine-tuning metabolic roles that optimize organ and …

Role of dietary fructose and hepatic de novo lipogenesis in fatty liver disease

S Softic, DE Cohen, CR Kahn - Digestive diseases and sciences, 2016 - Springer
Nonalcoholic fatty liver disease (NAFLD) is a liver manifestation of metabolic syndrome.
Overconsumption of high-fat diet (HFD) and increased intake of sugar-sweetened …

Beneficial effects of the ketogenic diet on nonalcoholic fatty liver disease: A comprehensive review of the literature

M Watanabe, R Tozzi, R Risi, D Tuccinardi… - Obesity …, 2020 - Wiley Online Library
Nonalcoholic fatty liver disease (NAFLD) is a major cause of chronic liver disease,
characterized by hepatic fat accumulation and possible development of inflammation …

An overview of lipid metabolism and nonalcoholic fatty liver disease

K Pei, T Gui, D Kan, H Feng, Y Jin… - BioMed Research …, 2020 - Wiley Online Library
The occurrence of nonalcoholic fatty liver disease (NAFLD) is associated with major
abnormalities of hepatic lipid metabolism. We propose that lipid abnormalities directly or …

Ketone bodies as signaling metabolites

JC Newman, E Verdin - Trends in Endocrinology & Metabolism, 2014 - cell.com
Traditionally, the ketone body β-hydroxybutyrate (βOHB) has been looked upon as a carrier
of energy from liver to peripheral tissues during fasting or exercise. However, βOHB also …

Nutritional ketosis for weight management and reversal of metabolic syndrome

VM Gershuni, SL Yan, V Medici - Current nutrition reports, 2018 - Springer
Abstract Purpose of Review The goal of this paper is to review current literature on
nutritional ketosis within the context of weight management and metabolic syndrome …

Dietary interventions: a promising treatment for polycystic ovary syndrome

X Che, Z Chen, M Liu, Z Mo - Annals of Nutrition and Metabolism, 2021 - karger.com
Background: Dietary interventions as a first-line treatment for patients with polycystic ovary
syndrome (PCOS) have been evaluated, but the optimal diet has not been determined …

A fad too far? Dietary strategies for the prevention and treatment of NAFLD

MP Moore, RP Cunningham, RJ Dashek, JM Mucinski… - …, 2020 - Wiley Online Library
Nonalcoholic fatty liver disease (NAFLD) is a major health problem, and its prevalence has
increased in recent years, concurrent with rising rates of obesity and other metabolic …

Interorgan metabolic crosstalk in human insulin resistance

S Gancheva, T Jelenik… - Physiological …, 2018 - journals.physiology.org
Excessive energy intake and reduced energy expenditure drive the development of insulin
resistance and metabolic diseases such as obesity and type 2 diabetes mellitus. Metabolic …