Obesity alters the ovarian proteomic response to zearalenone exposure

ME González-Alvarez, BC McGuire… - Biology of …, 2021 - academic.oup.com
Zearalenone (ZEN), a nonsteroidal estrogenic mycotoxin, is detrimental to female
reproduction. Altered chemical biotransformation, depleted primordial follicles and a blunted …

A draft map of the human ovarian proteome for tissue engineering and clinical applications

E Ouni, D Vertommen, MC Chiti, MM Dolmans… - Molecular & Cellular …, 2019 - ASBMB
Fertility preservation research in women today is increasingly taking advantage of
bioengineering techniques to develop new biomimetic materials and solutions to safeguard …

Pigment Epithelium-Derived Factor, a Novel Adipokine, Contributes to Gestational Diabetes Mellitus

W Qi, D Zhu, P Yin, X Gu, Z Zhao, M Li… - The Journal of …, 2024 - academic.oup.com
Context Excessive insulin resistance, inadequate insulin compensation, or both could result
in gestational diabetes mellitus (GDM). Levels of pigment epithelium-derived factor (PEDF) …

Therapeutic potential of pigment epithelium-derived factor in cancer

S Yamagishi, Y Koga, A Sotokawauchi… - Current …, 2019 - ingentaconnect.com
Pigment epithelium-derived factor (PEDF) is one of the serine protease inhibitors with
multifunctional properties, which is produced by various types of organs and tissues. There …

GnRH agonist triggering modulates PEDF to VEGF ratio inversely to hCG in granulosa cells

I Miller, D Chuderland, R Ron-El… - The Journal of …, 2015 - academic.oup.com
Context: GnRH agonist (GnRH-a) triggering is associated with a reduced risk of ovarian
hyperstimulation syndrome (OHSS) compared with human chorionic gonadotropin (hCG) in …

[HTML][HTML] Pigment epithelium-derived factor: clinical significance in estrogen-dependent tissues and its potential in cancer therapy

ML Franco-Chuaire, S Ramírez-Clavijo… - Iranian journal of …, 2015 - ncbi.nlm.nih.gov
Pigment epithelium-derived factor (PEDF) is a glycoprotein that belongs to the family of non-
inhibitory serpins. The broad spectrum of PEDF biological activity is evident when …

The family secrets of avian egg-specific ovalbumin and its related proteins Y and X

M Da Silva, S Beauclercq, G Harichaux… - Biology of …, 2015 - academic.oup.com
The ovalbumin gene family in Gallus gallus is composed of three homologous genes
located within a 46 kb locus on chromosome 2: ovalbumin, ovalbumin-related protein Y …

Elucidating the role of pigment epithelium-derived factor (PEDF) in metabolic PCOS models

M Silber, I Miller, H Bar-Joseph… - Journal of …, 2020 - joe.bioscientifica.com
PCOS is the most common endocrinopathy in women; associated with obesity and insulin
resistance (IR). IR leads to accumulation of advanced-glycation-end-products (AGEs) and …

The dual role of PEDF in the pathogenesis of OHSS: negating both angiogenic and inflammatory pathways

I Miller, D Chuderland, H Grossman… - The Journal of …, 2016 - academic.oup.com
Context: Ovarian hyperstimulation syndrome (OHSS) is a potentially life-threatening
complication of assisted reproductive technologies. This complex syndrome is known to …

Administration of pigment epithelium-derived factor inhibits airway inflammation and remodeling in chronic OVA-induced mice via VEGF suppression

W Zha, M Su, M Huang, J Cai… - Allergy, Asthma & …, 2016 - synapse.koreamed.org
Purpose Pigment epithelium-derived factor (PEDF) is a recently discovered
antiangiogenesis protein. PEDF possesses powerful anti-inflammatory, antioxidative …