From 1957 to nowadays: a brief history of epigenetics
P Peixoto, PF Cartron, AA Serandour… - International journal of …, 2020 - mdpi.com
Due to the spectacular number of studies focusing on epigenetics in the last few decades,
and particularly for the last few years, the availability of a chronology of epigenetics appears …
and particularly for the last few years, the availability of a chronology of epigenetics appears …
Hox genes in vertebrate development
R Krumlauf - Cell, 1994 - Elsevier
Organization and Evolution of Hox/HOM-C Complexes The genomic structural and
organizational similarities between vertebrate Hox and Drosophila HOM-C complexes …
organizational similarities between vertebrate Hox and Drosophila HOM-C complexes …
Selective recognition of methylated lysine 9 on histone H3 by the HP1 chromo domain
Abstract Heterochromatin protein 1 (HP1) is localized at heterochromatin sites where it
mediates gene silencing,. The chromo domain of HP1 is necessary for both targeting and …
mediates gene silencing,. The chromo domain of HP1 is necessary for both targeting and …
Methylation of histone H3 lysine 9 creates a binding site for HP1 proteins
M Lachner, D O'Carroll, S Rea, K Mechtler, T Jenuwein - Nature, 2001 - nature.com
Distinct modifications of histone amino termini, such as acetylation, phosphorylation and
methylation, have been proposed to underlie a chromatin-based regulatory mechanism, that …
methylation, have been proposed to underlie a chromatin-based regulatory mechanism, that …
AT-hook motifs identified in a wide variety of DNA-binding proteins
L Aravind, D Landsman - Nucleic acids research, 1998 - academic.oup.com
The AT-hook is a small DNA-binding protein motif which was first described in the high
mobility group non-histone chromosomal protein HMG-I (Y). Since its discovery, this motif …
mobility group non-histone chromosomal protein HMG-I (Y). Since its discovery, this motif …
The protein encoded by the Drosophila position‐effect variegation suppressor gene Su (var) 3‐9 combines domains of antagonistic regulators of homeotic gene …
B Tschiersch, A Hofmann, V Krauss, R Dorn… - The EMBO …, 1994 - embopress.org
Modifier mutations of position‐effect variegation (PEV) represent a useful tool for a genetic
and molecular dissection of genes connected with chromatin regulation in Drosophila. The …
and molecular dissection of genes connected with chromatin regulation in Drosophila. The …
The core of the polycomb repressive complex is compositionally and functionally conserved in flies and humans
SS Levine, A Weiss, H Erdjument-Bromage… - … and cellular biology, 2002 - Taylor & Francis
The Polycomb group (PcG) genes are required to maintain homeotic genes in a silenced
state during development in drosophila and mammals and are thought to form several …
state during development in drosophila and mammals and are thought to form several …
Compaction of chromatin by diverse Polycomb group proteins requires localized regions of high charge
DJ Grau, BA Chapman, JD Garlick… - Genes & …, 2011 - genesdev.cshlp.org
Polycomb group (PcG) proteins are required for the epigenetic maintenance of
developmental genes in a silent state. Proteins in the Polycomb-repressive complex 1 …
developmental genes in a silent state. Proteins in the Polycomb-repressive complex 1 …
KAP-1 corepressor protein interacts and colocalizes with heterochromatic and euchromatic HP1 proteins: a potential role for Krüppel-associated box–zinc finger …
RF Ryan, DC Schultz, K Ayyanathan… - … and cellular biology, 1999 - Am Soc Microbiol
Krüppel-associated box (KRAB) domains are present in approximately one-third of all
human zinc finger proteins (ZFPs) and are potent transcriptional repression modules. We …
human zinc finger proteins (ZFPs) and are potent transcriptional repression modules. We …
Heterochromatin formation in mammalian cells: interaction between histones and HP1 proteins
AL Nielsen, M Oulad-Abdelghani, JA Ortiz… - Molecular cell, 2001 - cell.com
Members of the heterochromatin protein 1 (HP1) family are silencing nonhistone proteins.
Here, we show that in P19 embryonal carcinoma (EC) nuclei, HP1 α, β, and γ form homo …
Here, we show that in P19 embryonal carcinoma (EC) nuclei, HP1 α, β, and γ form homo …