Nanomedicines harnessing cGAS-STING pathway: sparking immune revitalization to transform 'cold'tumors into 'hot'tumors
X Ying, Q Chen, Y Yang, Z Wu, W Zeng, C Miao… - Molecular Cancer, 2024 - Springer
Abstract cGAS-STING pathway stands at the forefront of innate immunity and plays a critical
role in regulating adaptive immune responses, making it as a key orchestrator of anti-tumor …
role in regulating adaptive immune responses, making it as a key orchestrator of anti-tumor …
Negative regulation of the IFI16 and cGAS DNA sensing pathways
S Muhič - 2022 - dspace.cuni.cz
DNA sensors are molecules with the ability to sense DNA constituting an important tool of
innate immunity. They are initiators of various signalling pathways, one of them being the …
innate immunity. They are initiators of various signalling pathways, one of them being the …
Sting agonists for treating bladder cancer and solid tumors
BF McGuinness, G Gallagher, MS McQueney… - US Patent …, 2024 - Google Patents
LOKCTEFSRHRXRJ-UHFFFAOYSA-I dipotassium trisodium dihydrogen phosphate
hydrogen phosphate dichloride Chemical compound P (= O)(O)(O)[O-].[K+]. P (= O)(O)([O …
hydrogen phosphate dichloride Chemical compound P (= O)(O)(O)[O-].[K+]. P (= O)(O)([O …
Sting agonists for treating bladder cancer and solid tumors
BF McGuinness, G Gallagher, MS McQueney… - US Patent …, 2021 - Google Patents
US11110106B2 - Sting agonists for treating bladder cancer and solid tumors - Google Patents
US11110106B2 - Sting agonists for treating bladder cancer and solid tumors - Google Patents …
US11110106B2 - Sting agonists for treating bladder cancer and solid tumors - Google Patents …
Sting agonists
DJ Diller, A Metzger, DE Kaelin Jr, S Paget… - US Patent …, 2021 - Google Patents
2019-11-19 Assigned to Venenum Biodesign, LLC reassignment Venenum Biodesign, LLC
ASSIGNMENT OF ASSIGNORS INTEREST (SEE DOCUMENT FOR DETAILS). Assignors …
ASSIGNMENT OF ASSIGNORS INTEREST (SEE DOCUMENT FOR DETAILS). Assignors …
Synthesis of 3', 5'-cyclic diguanylic acid (c-di-GMP) as mucosal vaccine adjuvant and bacterial second messenger
K Milah - 2018 - dr.library.brocku.ca
The present study describes the synthesis of 3', 5'-cyclic diguanylic acid (c-di-GMP), attempts
were made to synthesize guanosine bearing a 2'-O-(hexyn-6-yl)-and 2'-O-(6-azidohexyl) …
were made to synthesize guanosine bearing a 2'-O-(hexyn-6-yl)-and 2'-O-(6-azidohexyl) …