[HTML][HTML] Follicular fluid: a powerful tool for the understanding and diagnosis of polycystic ovary syndrome

AT Brinca, AC Ramalhinho, Â Sousa, AH Oliani… - Biomedicines, 2022 - mdpi.com
Polycystic ovary syndrome (PCOS) represents one of the leading causes of anovulatory
infertility and affects 5% to 20% of women worldwide. Until today, both the subsequent …

Ovarian environment aging: follicular fluid lipidomic and related metabolic pathways

FB Cordeiro, DA Montani, EJ Pilau, FC Gozzo… - Journal of Assisted …, 2018 - Springer
Purpose The decline in female fecundity with age may be caused by decreased oocyte
quality, a factor that may be associated with the altered composition of follicular fluid (FF) …

Current progress of lipid analysis in metabolic diseases by mass spectrometry methods

A Mika, T Sledzinski… - Current medicinal …, 2019 - ingentaconnect.com
Background: Obesity, insulin resistance, diabetes, and metabolic syndrome are associated
with lipid alterations, and they affect the risk of long-term cardiovascular disease. A reliable …

Multiple reaction monitoring (MRM)‐profiling for biomarker discovery applied to human polycystic ovarian syndrome

FB Cordeiro, CR Ferreira, TJP Sobreira… - Rapid …, 2017 - Wiley Online Library
Rationale We describe multiple reaction monitoring (MRM)‐profiling, which provides
accelerated discovery of discriminating molecular features, and its application to human …

Targeted metabolomics reveals reduced levels of polyunsaturated choline plasmalogens and a smaller dimethylarginine/arginine ratio in the follicular fluid of patients …

JMC de la Barca, T Boueilh, G Simard… - Human …, 2017 - academic.oup.com
ABSTRACT STUDY QUESTION Does the metabolomic profile of the follicular fluid (FF) of
patients with a diminished ovarian reserve (DOR) differ from that of patients with a normal …

Hyper response to ovarian stimulation affects the follicular fluid metabolomic profile of women undergoing IVF similarly to polycystic ovary syndrome

FB Cordeiro, TR Cataldi, BZ de Souza, RC Rochetti… - Metabolomics, 2018 - Springer
Introduction During in vitro fertilization (IVF), the hyper response to controlled ovarian
stimulation (COS) is a common characteristic among patients diagnosed with polycystic …

Nontargeted metabolomics analysis of follicular fluid in patients with endometriosis provides a new direction for the study of oocyte quality

Y Wei, Z Zhang, Y Zhang, J Li, X Ruan, Q Wan… - MedComm, 2023 - Wiley Online Library
Endometriosis is a common, estrogen‐dependent chronic gynecological disease that
endangers the reproductive system and systemic metabolism of patients. We aimed to …

Upregulated ribosomal pathway impairs follicle development in a polycystic ovary syndrome mouse model: differential gene expression analysis of oocytes

N Nakanishi, S Osuka, T Kono, H Kobayashi… - Reproductive …, 2023 - Springer
Polycystic ovary syndrome (PCOS), a common endocrine disorder, is associated with
impaired oocyte development, leading to infertility. However, the pathogenesis of PCOS has …

Distinct localisation of lipids in the ovarian follicular environment

T Pantasri, LL Wu, ML Hull, TR Sullivan… - Reproduction …, 2015 - CSIRO Publishing
Obesity is associated with decreased pregnancy rates due, in part, to compromised oocyte
quality. The aim of the present cross-sectional study of 84 women undergoing oocyte …

[HTML][HTML] Lipidomics analysis of human follicular fluid form normal-weight patients with polycystic ovary syndrome: a pilot study

Y Ban, H Ran, Y Chen, L Ma - Journal of Ovarian Research, 2021 - Springer
Background The polycystic ovary syndrome (PCOS) is the most common endocrine
associated with insulin resistance, even in the absence of overweight. The global lipid …