The most recent updated classification of inborn errors of immunity/primary
immunodeficiencies, compiled by the International Union of Immunological Societies Expert …

Monogenic autoinflammatory diseases are a group of rheumatologic disorders caused by
dysregulation in the innate immune system. The molecular mechanisms of these disorders …

We report the updated classification of inborn errors of immunity, compiled by the
International Union of Immunological Societies Expert Committee. This report documents the …

Meningeal lymphatic vessels (mLVs) have been shown to be involved in amyloid beta (Aβ)
clearance, which is considered as a potential therapeutic target for Alzheimer's disease …

Abstract Proteins of the Wiskott-Aldrich syndrome protein (WASP) family play a central role
in regulating actin cytoskeletal dynamics in a wide range of cellular processes. Genetic …

The actin cytoskeleton is composed of dynamic filament networks that build adaptable local
architectures to sustain nearly all cellular activities in response to a myriad of stimuli …

Inborn errors of immunity (IEIs) are immunological disorders characterized by variable
susceptibility to infections, immune dysregulation and/or malignancies, as a consequence of …

INTRODUCTION The essential role of actin cytoskeletal regulatory proteins in expression of
effective immune responses is exemplified by the impaired immunity manifested by patients …

New primary immunodeficiencies 2021 context and future : Current Opinion in Pediatrics New
primary immunodeficiencies 2021 context and future : Current Opinion in Pediatrics Log in or …

Background Genome-wide association studies (GWAS) have identified more than 200
breast cancer risk-associated genetic loci, yet the causal genes and biological mechanisms …