This review outlines the most recent papers describing the stereoselective synthesis of γ-
amino acids. In this update, the γ-amino acids have been classified according to the type of …

Crystallographic investigations deliver high-accuracy information about positions of atoms in
crystal unit cells. For chemists, however, the structure of a molecule is most often of interest …

Despite their concomitant emergence in the 1990s, γ‐peptide foldamers have not developed
as fast as β‐peptide foldamers and to date, only a few γ‐oligomer structures have been …

Apratoxins are cytotoxic natural products originally isolated from marine cyanobacteria that
act by preventing cotranslational translocation early in the secretory pathway to …

Double helices are not common in polypeptides and proteins except in the peptide antibiotic
gramicidin A and analogous l, d‐peptides. In contrast to natural polypeptides, remarkable β …

Chirality is ubiquitous in nature, and homochirality is manifested in many biomolecules.
Although β‐double helices are rare in peptides and proteins, they consist of alternating L …

The α, β‐unsaturated γ‐lactams have been found in many biologically active peptide natural
products. Due to their biological activities, extensive efforts have been made in the literature …

A novel, ultrafast, mild and scalable amide bond formation strategy in methanol using simple
thioacids and amines is described. The mechanism suggests that the coupling reactions are …

Numerous strategies have been developed to mimic the α-helical secondary structure using
hybrid peptides containing non-natural amino acids. In contrast to the β-and α/β-hybrid …

Synthesis, crystal conformations of α/γ4-hybrid peptide helices containing proteinogenic
amino acid side-chains, and the analogy with the α-helix are reported. Results suggest that …