Modern approaches in the discovery and development of plant-based natural products and their analogues as potential therapeutic agents
Natural products represents an important source of new lead compounds in drug discovery
research. Several drugs currently used as therapeutic agents have been developed from …
research. Several drugs currently used as therapeutic agents have been developed from …
Recent molecular mechanisms and beneficial effects of phytochemicals and plant-based whole foods in reducing LDL-C and preventing cardiovascular disease
Abnormal lipid metabolism leads to the development of hyperlipidemia, a common cause of
multiple chronic disorders, including cardiovascular disease (CVD), obesity, diabetes, and …
multiple chronic disorders, including cardiovascular disease (CVD), obesity, diabetes, and …
In silico investigations identified Butyl Xanalterate to competently target CK2α (CSNK2A1) for therapy of chronic lymphocytic leukemia
Chronic lymphocytic leukemia (CLL) is an incurable malignancy of B-cells. In this study,
bioinformatics analyses were conducted to identify possible pathogenic roles of CK2α …
bioinformatics analyses were conducted to identify possible pathogenic roles of CK2α …
Lycopene amends LPS induced oxidative stress and hypertriglyceridemia via modulating PCSK-9 expression and Apo-CIII mediated lipoprotein lipase activity
This study was undertaken to uncover the regulatory role of lycopene in targeting
lipopolysaccharide (LPS) induced oxidative stress and inflammatory cascades and …
lipopolysaccharide (LPS) induced oxidative stress and inflammatory cascades and …
Potential role of lycopene in targeting proprotein convertase subtilisin/kexin type-9 to combat hypercholesterolemia
Proprotein convertase subtilisin/kexin type 9 (PCSK-9) is a serine protease of the proprotien
convertase (PC) family that has profound effects on plasma low density lipoprotein …
convertase (PC) family that has profound effects on plasma low density lipoprotein …
Cationic nanoparticles for treatment of neurological diseases
Recently, several nutraceutical products are being explored to validate their neuroprotective
claims as well as clinical prospects in terms of balancing neurosignaling mechanisms …
claims as well as clinical prospects in terms of balancing neurosignaling mechanisms …
Traditional management of diabetes in Pakistan: ethnobotanical investigation from traditional health practitioners
Ethnopharmacological relevance The uses of anti-diabetic plants are well anchored in the
traditional health care system of Pakistan. To the best of our knowledge, this is the first ethno …
traditional health care system of Pakistan. To the best of our knowledge, this is the first ethno …
Multitargeted virtual screening and molecular simulation of natural product-like compounds against GSK3β, NMDA-receptor, and BACE-1 for the management of …
The complexity of Alzheimer's disease (AD) and several side effects of currently available
medication inclined us to search for a novel natural cure by targeting multiple key regulatory …
medication inclined us to search for a novel natural cure by targeting multiple key regulatory …
Myco-synthesis of silver nanoparticles and their bioactive role against pathogenic microbes
Simple Summary The relatively high prevalence of microbial infections and the rising
resistance to traditional antibiotics are the causes of the need for revolutionary antibiotics …
resistance to traditional antibiotics are the causes of the need for revolutionary antibiotics …
Assessment of the potential health benefits of certain total extracts from Vitis vinifera, Aesculus hyppocastanum and Curcuma longa
A number of recent studies have illustrated the active role of food/natural components in the
prevention of chronic diseases and in the improvement of the quality of life. In the present …
prevention of chronic diseases and in the improvement of the quality of life. In the present …