Quercetin is a flavonoid with notable pharmacological effects and promising therapeutic
potential. It is widely distributed among plants and found commonly in daily diets …

The goal of this review article is to provide a resource for longitudinal studies, using animal
models, directed at understanding and modifying the relationship between cognition and …

The cerebrospinal fluid (CSF) features a unique immune cell composition and is in constant
contact with the brain borders, thus permitting insights into the brain to diagnose and monitor …

Melatonin (MLT) is a neurohormone that is regulated by the circadian clock and plays
multifunctional roles in numerous neurodegenerative disorders, such as Alzheimer's …

Alzheimer's disease (AD) is an irreversible, progressive disease that slowly destroys
cognitive function, such as thinking, remembering, and reasoning, to a level that one cannot …

Alzheimer´ s disease (AD) and related forms of dementia are increasingly affecting the aging
population throughout the world, at an alarming rate. The World Alzheimer´ s Report …

Mitochondrial dysfunction results in a series of defective cellular events, including
decreased adenosine triphosphate (ATP) production, enhanced reactive oxygen species …

Alzheimer's disease (AD) is an irrevocable chronic brain disorder featured by neuronal loss,
microglial accumulation, and progressive cognitive impairment. The proper pathophysiology …

Amyloid-beta (Aβ) plays an important role in the pathogenesis of Alzheimer's disease.
Aberrant Aβ accumulation induces neuroinflammation, cerebrovascular alterations, and …

The development and characterization of new improved animal models is pivotal in
Alzheimer's Disease (AD) research, since valid models enable the identification of early …