Neuroinflammatory mechanisms in ischemic stroke: focus on cardioembolic stroke, background, and therapeutic approaches

CD Maida, RL Norrito, M Daidone… - International journal of …, 2020 - mdpi.com
One of the most important causes of neurological morbidity and mortality in the world is
ischemic stroke. It can be a result of multiple events such as embolism with a cardiac origin …

Neuroinflammation in post-ischemic neurodegeneration of the brain: friend, foe, or both?

R Pluta, S Januszewski, SJ Czuczwar - International Journal of Molecular …, 2021 - mdpi.com
One of the leading causes of neurological mortality, disability, and dementia worldwide is
cerebral ischemia. Among the many pathological phenomena, the immune system plays an …

Ischemic stroke genetics: what is new and how to apply it in clinical practice?

A Ekkert, A Šliachtenko, J Grigaitė, B Burnytė, A Utkus… - Genes, 2021 - mdpi.com
The etiology of ischemic stroke is multifactorial. Although receiving less emphasis, genetic
causes make a significant contribution to ischemic stroke genesis, especially in early-onset …

Molecular mechanisms of inflammasome in ischemic stroke pathogenesis

MG Puleo, S Miceli, T Di Chiara, GM Pizzo… - Pharmaceuticals, 2022 - mdpi.com
Ischemic stroke (also called cerebral ischemia) is one of the leading causes of death and
severe disability worldwide. NLR inflammasomes play a crucial role in sensing cell damage …

FSAP aggravated endothelial dysfunction and neurological deficits in acute ischemic stroke due to large vessel occlusion

DS Tian, C Qin, LQ Zhou, S Yang, M Chen… - … and Targeted Therapy, 2022 - nature.com
Revascularization and angiogenesis, as substrates of sustained collateral circulation, play a
crucial role in determining the severity and clinical outcome of acute ischemic stroke (AIS) …

Eating behaviors, lifestyle, and ischemic stroke: a Lebanese case-control study

E Maalouf, S Hallit, P Salameh, H Hosseini - International Journal of …, 2023 - mdpi.com
Background: Stroke is the second leading cause of death and the third leading cause of
disability on a global scale. Most clinicians tend to underestimate the importance of diet and …

Brain immune interactions—novel emerging options to treat acute ischemic brain injury

S Muhammad, SR Chaudhry, UD Kahlert, M Niemelä… - Cells, 2021 - mdpi.com
Ischemic stroke is still among the leading causes of mortality and morbidity worldwide.
Despite intensive advancements in medical sciences, the clinical options to treat ischemic …

Molecular biology of atherosclerotic ischemic strokes

A Tuttolomondo, MG Puleo, MC Velardo… - International journal of …, 2020 - mdpi.com
Among the causes of global death and disability, ischemic stroke (also known as cerebral
ischemia) plays a pivotal role, by determining the highest number of worldwide mortality …

Stroke and etiopathogenesis: what is known?

T Ciarambino, P Crispino, E Mastrolorenzo, A Viceconti… - Genes, 2022 - mdpi.com
Background: A substantial portion of stroke risk remains unexplained, and a contribution
from genetic factors is supported by recent findings. In most cases, genetic risk factors …

Circulating MiRNA-195-5p and-451a in diabetic patients with transient and acute ischemic stroke in the emergency department

M Giordano, MC Trotta, T Ciarambino… - International Journal of …, 2020 - mdpi.com
(1) Background: Circulating micro-RNAs (miRNAs) modulate the expression of molecules in
diabetes. We evaluated the expression of serum miRNA-195-5p and-451a in diabetic …