Obesity, kidney dysfunction and hypertension: mechanistic links

JE Hall, JM do Carmo, AA da Silva, Z Wang… - Nature reviews …, 2019 - nature.com
Excessive adiposity raises blood pressure and accounts for 65–75% of primary
hypertension, which is a major driver of cardiovascular and kidney diseases. In obesity …

The hematologic consequences of obesity

JC Purdy, JJ Shatzel - European journal of haematology, 2021 - Wiley Online Library
The prevalence of obesity is increasing and progressively influencing physician‐patient
interactions. While there is a sizable amount of data demonstrating that obesity is a state of …

Obesity, kidney dysfunction, and inflammation: interactions in hypertension

JE Hall, AJ Mouton, AA da Silva… - Cardiovascular …, 2021 - academic.oup.com
Abstract Obesity contributes 65–75% of the risk for human primary (essential) hypertension
(HT) which is a major driver of cardiovascular and kidney diseases. Kidney dysfunction …

Association of metabolic syndrome and chronic kidney disease

FG Scurt, MJ Ganz, C Herzog, K Bose… - Obesity …, 2024 - Wiley Online Library
The prevalence of kidney disease is increasing rapidly worldwide, reflecting rising rates of
obesity, diabetes, and associated metabolic syndrome (MetS). Chronic kidney disease and …

The link between obstructive sleep apnea and cardiovascular disease

F Bauters, ER Rietzschel, KBC Hertegonne… - Current atherosclerosis …, 2016 - Springer
Obstructive sleep apnea (OSA) is common in the general population and highly prevalent in
patients with cardiovascular disease. In this paper, we review (1) the pathophysiological …

Sympathetic activation in cardiovascular disease: evidence, clinical impact and therapeutic implications

G Grassi, G Seravalle, G Mancia - European journal of clinical …, 2015 - Wiley Online Library
Background The sympathetic nervous exerts a key role in cardiovascular homeostasis
control by regulating cardiac output, systemic vascular resistance, heart rate and blood …

Anti-inflammatory effects of melatonin in obesity and hypertension

NJ Prado, L Ferder, W Manucha, ER Diez - Current hypertension reports, 2018 - Springer
Abstract Purpose of Review Here, we review the known relations between hypertension and
obesity to inflammation and postulate the endogenous protective effect of melatonin and its …

[HTML][HTML] The sympathetic nervous system and catecholamines metabolism in obstructive sleep apnoea

V Bisogni, MF Pengo, G Maiolino… - Journal of thoracic …, 2016 - ncbi.nlm.nih.gov
Obstructive sleep apnoea (OSA) is the most common sleep disorder of breathing in middle-
aged and overweight subjects. It features recurrent episodes of upper airway total (apnoea) …

Body temperature and sleep

R Szymusiak - Handbook of clinical neurology, 2018 - Elsevier
Sleep in mammals is accompanied by a decrease in core body temperature (CBT). The
circadian clock in the hypothalamic suprachiasmatic nucleus regulates daily rhythms in both …

Beyond resistant hypertension: relationship between refractory hypertension and obstructive sleep apnea

MA Martínez-García, C Navarro-Soriano, G Torres… - …, 2018 - Am Heart Assoc
Obstructive sleep apnea (OSA) is an independent cause of resistant hypertension (RH) but
its association with refractory hypertension (RfH), a recently described form of severe …