Aspergillus fumigatus and Aspergillosis in 2019

JP Latgé, G Chamilos - Clinical microbiology reviews, 2019 - Am Soc Microbiol
Aspergillus fumigatus is a saprotrophic fungus; its primary habitat is the soil. In its ecological
niche, the fungus has learned how to adapt and proliferate in hostile environments. This …

Mechanisms of fungal dissemination

AB Strickland, M Shi - Cellular and Molecular Life Sciences, 2021 - Springer
Fungal infections are an increasing threat to global public health. There are more than six
million fungal species worldwide, but less than 1% are known to infect humans. Most of …

The rise in cases of mucormycosis, candidiasis and aspergillosis amidst COVID19

A Ghosh, A Sarkar, P Paul, P Patel - Fungal biology reviews, 2021 - Elsevier
The Coronavirus outbreak globally has changed the medical system and also led to a
shortage of medical facilities in both developing and underdeveloped countries. The …

Human airway epithelium responses to invasive fungal infections: A critical partner in innate immunity

AJ Crossen, RA Ward, JL Reedy, MV Surve, BS Klein… - Journal of Fungi, 2022 - mdpi.com
The lung epithelial lining serves as the primary barrier to inhaled environmental toxins,
allergens, and invading pathogens. Pulmonary fungal infections are devastating and carry …

Bronchial Epithelial Cells on the Front Line to Fight Lung Infection-Causing Aspergillus fumigatus

J Bigot, L Guillot, J Guitard, M Ruffin, H Corvol… - Frontiers in …, 2020 - frontiersin.org
Aspergillus fumigatus is an environmental filamentous fungus that can be pathogenic for
humans, wherein it is responsible for a large variety of clinical forms ranging from allergic …

EphA2-Dependent Internalization of A. fumigatus Conidia in A549 Lung Cells Is Modulated by DHN-Melanin

EM Keizer, HAB Wösten, H de Cock - Frontiers in Microbiology, 2020 - frontiersin.org
Dectin-1 and ephrin type-A receptor 2 (EphA2) receptors recognize β-glucan present in the
fungal cell wall. Inhibition of Dectin-1 with the monoclonal 2a11 antibody was shown to …

Respiratory epithelial cells: more than just a physical barrier to fungal infections

BCSC Barros, BR Almeida, DTL Barros, MS Toledo… - Journal of Fungi, 2022 - mdpi.com
The respiratory epithelium is highly complex, and its composition varies along the
conducting airways and alveoli. In addition to their primary function in maintaining the …

ITPK1 Sensitizes Tumor Cells to IgA-dependent Neutrophil Killing In Vivo

CA Richterich, MEW Logtenberg… - The Journal of …, 2024 - journals.aai.org
Neutrophils can efficiently trigger cytotoxicity toward tumor cells and other target cells upon
engagement of the IgA receptor CD89. However, the cell-intrinsic factors that influence the …

In silico identification and functional study of long non-coding RNA involved in acute hepatopancreatic necrosis disease caused by Vibrio parahaemolyticus infection …

P Olasard, P Suksri, C Taneerat… - Fish & Shellfish …, 2024 - Elsevier
Acute hepatopancreatic necrosis disease (AHPND) caused by toxin-producing Vibrio
parahaemolyticus (Vp AHPND) has severely affected shrimp production. Long non-coding …

PCSK9i promoting the transformation of AS plaques into a stable plaque by targeting the miR-186-5p/Wipf2 and miR-375-3p/Pdk1/Yap1 in ApoE−/− mice

Y Zhao, N Liu, J Zhang, L Zhao - Frontiers in Medicine, 2024 - frontiersin.org
Background Atherosclerosis (AS) is a multifaceted disease characterized by disruptions in
lipid metabolism, vascular inflammation, and the involvement of diverse cellular constituents …