The third edition of Flow Cytometry Guidelines provides the key aspects to consider when
performing flow cytometry experiments and includes comprehensive sections describing …

Autoimmune T cell responses directed against insulin-producing β cells are central to the
pathogenesis of type 1 diabetes (T1D). Detection of such responses is therefore critical to …

The engineering of autologous patient T cells for adoptive cell therapies has revolutionized
the treatment of several types of cancer. However, further improvements are needed to …

These guidelines are a consensus work of a considerable number of members of the
immunology and flow cytometry community. They provide the theory and key practical …

Human leukocyte antigen (HLA)-independent, T cell–mediated targeting of cancer cells
would allow immune destruction of malignancies in all individuals. Here, we use genome …

The ability to decode antigen specificities encapsulated in the sequences of rearranged T-
cell receptor (TCR) genes is critical for our understanding of the adaptive immune system …

Allergen-specific type 2 helper T (TH2) cells play a central role in initiating and orchestrating
the allergic and asthmatic inflammatory response pathways. One major factor limiting the …

Influenza is a deadly and costly infectious disease, even during flu seasons when an
effective vaccine has been developed. To improve vaccines against respiratory viruses, a …

Adoptively transferred tumor-infiltrating T lymphocytes (TILs) that mediate complete
regression of metastatic melanoma have been shown to recognize mutated epitopes …

Fluorescently labeled multimeric complexes of peptide-MHC, the molecular entities
recognized by the T cell receptor, have become essential reagents for detection of antigen …