[HTML][HTML] Enhancing the therapeutic efficacy of nanoparticles for cancer treatment using versatile targeted strategies
Poor targeting of therapeutics leading to severe adverse effects on normal tissues is
considered one of the obstacles in cancer therapy. To help overcome this, nanoscale drug …
considered one of the obstacles in cancer therapy. To help overcome this, nanoscale drug …
Application of glutathione depletion in cancer therapy: Enhanced ROS-based therapy, ferroptosis, and chemotherapy
B Niu, K Liao, Y Zhou, T Wen, G Quan, X Pan, C Wu - Biomaterials, 2021 - Elsevier
Glutathione (GSH) is an important member of cellular antioxidative system. In cancer cells, a
high level of GSH is indispensable to scavenge excessive reactive oxygen species (ROS) …
high level of GSH is indispensable to scavenge excessive reactive oxygen species (ROS) …
[HTML][HTML] Recent progress in ferroptosis: inducers and inhibitors
Y Du, Z Guo - Cell death discovery, 2022 - nature.com
Ferroptosis is a new iron-dependent form of programmed cell death characterized by iron
accumulation and lipid peroxidation. In recent years, ferroptosis has garnered enormous …
accumulation and lipid peroxidation. In recent years, ferroptosis has garnered enormous …
Manipulating intratumoral fenton chemistry for enhanced chemodynamic and chemodynamic‐synergized multimodal therapy
Chemodynamic therapy (CDT) uses the tumor microenvironment‐assisted intratumoral
Fenton reaction for generating highly toxic hydroxyl free radicals (• OH) to achieve selective …
Fenton reaction for generating highly toxic hydroxyl free radicals (• OH) to achieve selective …
Engineering nanomedicine for glutathione depletion-augmented cancer therapy
Y Xiong, C Xiao, Z Li, X Yang - Chemical Society Reviews, 2021 - pubs.rsc.org
Glutathione (GSH), the main redox buffer, has long been recognized as a pivotal modulator
of tumor initiation, progression and metastasis. It is also implicated in the resistance of …
of tumor initiation, progression and metastasis. It is also implicated in the resistance of …
Biomedicine meets Fenton chemistry
Since the first connection between Fenton chemistry and biomedicine, numerous studies
have been presented in this field. Comprehensive presentation of the guidance from Fenton …
have been presented in this field. Comprehensive presentation of the guidance from Fenton …
Ferric-ellagate complex: A promising multifunctional photocatalyst
B Xue, Q Li, L Wang, M Deng, H Zhou, N Li, M Tan… - Chemosphere, 2023 - Elsevier
The semiconductors have exhibited great potential in the field of photocatalytic energy
production, environmental remediation and bactericidal. Nevertheless, those inorganic …
production, environmental remediation and bactericidal. Nevertheless, those inorganic …
Tumor‐microenvironment‐activated reactive oxygen species amplifier for enzymatic cascade cancer starvation/chemodynamic/immunotherapy
M Wang, M Chang, C Li, Q Chen, Z Hou… - Advanced …, 2022 - Wiley Online Library
At present, some progress has been made in the field of cancer theranostics based on
nanocatalysts (NCs), but achieving precise theranostics in response to the specific tumor …
nanocatalysts (NCs), but achieving precise theranostics in response to the specific tumor …
Polyphenol‐containing nanoparticles: synthesis, properties, and therapeutic delivery
Polyphenols, the phenolic hydroxyl group‐containing organic molecules, are widely found in
natural plants and have shown beneficial effects on human health. Recently, polyphenol …
natural plants and have shown beneficial effects on human health. Recently, polyphenol …
Recent progress of chemodynamic therapy-induced combination cancer therapy
Chemodynamic therapy (CDT) is an emerging cancer treatment strategy that uses CDT
agents to convert hydrogen peroxide (H 2 O 2) into the hydroxyl radical (radical dotOH), the …
agents to convert hydrogen peroxide (H 2 O 2) into the hydroxyl radical (radical dotOH), the …