[HTML][HTML] Enhancing the therapeutic efficacy of nanoparticles for cancer treatment using versatile targeted strategies

H Tian, T Zhang, S Qin, Z Huang, L Zhou, J Shi… - Journal of hematology & …, 2022 - Springer
Poor targeting of therapeutics leading to severe adverse effects on normal tissues is
considered one of the obstacles in cancer therapy. To help overcome this, nanoscale drug …

Application of glutathione depletion in cancer therapy: Enhanced ROS-based therapy, ferroptosis, and chemotherapy

B Niu, K Liao, Y Zhou, T Wen, G Quan, X Pan, C Wu - Biomaterials, 2021 - Elsevier
Glutathione (GSH) is an important member of cellular antioxidative system. In cancer cells, a
high level of GSH is indispensable to scavenge excessive reactive oxygen species (ROS) …

[HTML][HTML] Recent progress in ferroptosis: inducers and inhibitors

Y Du, Z Guo - Cell death discovery, 2022 - nature.com
Ferroptosis is a new iron-dependent form of programmed cell death characterized by iron
accumulation and lipid peroxidation. In recent years, ferroptosis has garnered enormous …

Manipulating intratumoral fenton chemistry for enhanced chemodynamic and chemodynamic‐synergized multimodal therapy

Y Zhou, S Fan, L Feng, X Huang, X Chen - Advanced Materials, 2021 - Wiley Online Library
Chemodynamic therapy (CDT) uses the tumor microenvironment‐assisted intratumoral
Fenton reaction for generating highly toxic hydroxyl free radicals (• OH) to achieve selective …

Engineering nanomedicine for glutathione depletion-augmented cancer therapy

Y Xiong, C Xiao, Z Li, X Yang - Chemical Society Reviews, 2021 - pubs.rsc.org
Glutathione (GSH), the main redox buffer, has long been recognized as a pivotal modulator
of tumor initiation, progression and metastasis. It is also implicated in the resistance of …

Biomedicine meets Fenton chemistry

Z Tang, P Zhao, H Wang, Y Liu, W Bu - Chemical reviews, 2021 - ACS Publications
Since the first connection between Fenton chemistry and biomedicine, numerous studies
have been presented in this field. Comprehensive presentation of the guidance from Fenton …

Ferric-ellagate complex: A promising multifunctional photocatalyst

B Xue, Q Li, L Wang, M Deng, H Zhou, N Li, M Tan… - Chemosphere, 2023 - Elsevier
The semiconductors have exhibited great potential in the field of photocatalytic energy
production, environmental remediation and bactericidal. Nevertheless, those inorganic …

Tumor‐microenvironment‐activated reactive oxygen species amplifier for enzymatic cascade cancer starvation/chemodynamic/immunotherapy

M Wang, M Chang, C Li, Q Chen, Z Hou… - Advanced …, 2022 - Wiley Online Library
At present, some progress has been made in the field of cancer theranostics based on
nanocatalysts (NCs), but achieving precise theranostics in response to the specific tumor …

Polyphenol‐containing nanoparticles: synthesis, properties, and therapeutic delivery

Y Guo, Q Sun, FG Wu, Y Dai, X Chen - Advanced Materials, 2021 - Wiley Online Library
Polyphenols, the phenolic hydroxyl group‐containing organic molecules, are widely found in
natural plants and have shown beneficial effects on human health. Recently, polyphenol …

Recent progress of chemodynamic therapy-induced combination cancer therapy

X Wang, X Zhong, Z Liu, L Cheng - Nano Today, 2020 - Elsevier
Chemodynamic therapy (CDT) is an emerging cancer treatment strategy that uses CDT
agents to convert hydrogen peroxide (H 2 O 2) into the hydroxyl radical (radical dotOH), the …